Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10571146 | 0.89 | ALDH1A1 (0.56) | ALDH1A1HTTKMT2AMEN1MT-CO2 | |
| SCHEMBL10569075 | 0.87 | ALDH1A1 (0.55) | ALDH1A1HTTKMT2AMEN1MT-CO2 | |
| SCHEMBL10572666 | 0.87 | ALDH1A1 (0.55) | ALDH1A1HTTKMT2AMEN1MT-CO2 | |
| SCHEMBL10569185 | 0.78 | ALDH1A1 (0.38) | ALDH1A1HTTKMT2AMEN1MT-CO2 | |
| SCHEMBL10567104 | 0.74 | SLC6A2 (0.45) | ALDH1A1KMT2AMEN1MT-CO2ALOX5 | |
| SCHEMBL10567917 | 0.74 | MT-CO2 (0.63) | ALDH1A1KMT2AMEN1MT-CO2ALOX5 | |
| SCHEMBL10567658 | 0.74 | ADRA1B (0.42) | ALDH1A1KMT2AMEN1AADATTSHR | |
| SCHEMBL10571010 | 0.73 | ALDH1A1 (0.49) | ALDH1A1KMT2AMEN1AADATNPC1 | |
| SCHEMBL10567008 | 0.71 | MEN1 (0.50) | ALDH1A1KMT2AMEN1MT-CO2ALOX5 | |
| SCHEMBL10569196 | 0.70 | MAPT (0.43) | ALDH1A1KMT2AMEN1HTR1AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4847285-A | 1-substituted phenyl-3-substituted methyl-pyrrolidine-2,5-diones and plant fungicide compositions containing same | THE DOW CHEMICAL COMPANY (US) | 1989-07-11 | — | — | US | disclosed |