Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 6/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10562286 | 0.91 | MAOB (0.51) | MAOBFFAR1FFAR4TSHRTBXAS1 | |
| SCHEMBL10565958 | 0.87 | ALDH1A1 (0.46) | MAOBNPC1RAB9ASMN1; SMN2TSHR | |
| SCHEMBL10563757 | 0.86 | MAPT (0.46) | MAOBFFAR1FFAR4MAOANPC1 | |
| SCHEMBL4415159 | 0.83 | TSHR (0.50) | MAOBFFAR1FFAR4NPC1SMN1; SMN2 | |
| Methane SCHEMBL10565161 | 0.82 | TSHR (0.49) | MAOBFFAR1FFAR4NPC1SMN1; SMN2 | |
| SCHEMBL13939925 | 0.81 | MAPT (0.54) | MAOBMAOANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10565152 | 0.79 | MAPT (0.46) | MAOBFFAR1FFAR4TBXAS1ALDH1A1 | |
| SCHEMBL10564870 | 0.79 | RXRA (0.61) | MAOBFFAR1 | |
| SCHEMBL10564536 | 0.78 | PTGS1 (0.49) | MAOBFFAR1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4417759 | 0.76 | ALDH1A1 (0.48) | NPC1RAB9ASMN1; SMN2TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4816591-A | 6,11-dihydrodibenz[b,e]oxepin-acetic acids and derivatives | AMERICAN HOECHST CORPORATION (US) | 1989-03-28 | — | — | US | disclosed |
| US-4585788-A | 6,11-dihydrodibenz[b,e]oxepin-acetic acids and derivatives | AMERICAN HOECHST CORPORATION (US) | 1986-04-29 | — | — | US | disclosed |
| US-4082850-A | TOPICAL APPLICATION OF A 6,11-DIHYDROBENZ(B,E)OXEPIN-ALKANOIC ACID OR DERIVATIVES THEREOF | AMERICAN HOECHST CORPORATION (US) | 1978-04-04 | — | — | US | disclosed |