Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.46 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.45 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methane SCHEMBL10565161 | 0.99 | TSHR (0.49) | TSHRALDH1A1HPGDMAPK10NR1H4 | |
| SCHEMBL4417759 | 0.93 | ALDH1A1 (0.48) | TSHRALDH1A1HPGDMAPK10L3MBTL1 | |
| SCHEMBL7275027 | 0.87 | TSHR (0.53) | TSHRALDH1A1MAPK10NR1H4L3MBTL1 | |
| SCHEMBL7275470 | 0.86 | TSHR (0.51) | TSHRALDH1A1MAPK10NR1H4L3MBTL1 | |
| SCHEMBL4057078 | 0.85 | TSHR (0.57) | TSHRALDH1A1MAPK10NR1H4SMN1; SMN2 | |
| SCHEMBL10565958 | 0.84 | ALDH1A1 (0.46) | TSHRALDH1A1HPGDL3MBTL1TBXAS1 | |
| SCHEMBL7274960 | 0.83 | TSHR (0.51) | TSHRALDH1A1HPGDMAPK10NR1H4 | |
| SCHEMBL10567154 | 0.83 | MAOB (0.51) | TSHRALDH1A1TBXAS1SMN1; SMN2NPC1 | |
| SCHEMBL10562286 | 0.83 | MAOB (0.51) | TSHRTBXAS1MAOBFFAR1FFAR4 | |
| SCHEMBL10565152 | 0.83 | MAPT (0.46) | ALDH1A1HPGDALOX5TBXAS1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2058294-B1 | METHOD FOR PRODUCING 2-(4-METHOXYCARBONYLMETHYLPHENOXYMETHYL)BENZOIC ACID METHYL ESTER | SUMITOMO CHEMICAL CO (JP) | 2013-01-02 | — | — | EP | disclosed |
| EP-2058294-B1 | METHOD FOR PRODUCING 2-(4-METHOXYCARBONYLMETHYLPHENOXYMETHYL)BENZOIC ACID METHYL ESTER | SUMITOMO CHEMICAL CO (JP) | 2013-01-02 | — | — | EP | disclosed |
| US-7687646-B2 | Polymorphic forms of olopatadine hydrochloride and methods for producing olopatadine and salts thereof | AZAD PHARMACEUTICAL INGREDIENTS, AG (CH) | 2010-03-30 | — | — | US | disclosed |
| US-7687646-B2 | Polymorphic forms of olopatadine hydrochloride and methods for producing olopatadine and salts thereof | AZAD PHARMACEUTICAL INGREDIENTS, AG (CH) | 2010-03-30 | — | — | US | disclosed |
| EP-2058294-A1 | 2-(4-METHOXYCARBONYLMETHYLPHENOXYMETHYL)BENZOIC ACID METHYL ESTER AND METHOD FOR PRODUCING THE SAME | Sumitomo Chemical Company, Limited (JP) | 2009-05-13 | — | — | EP | disclosed |
| EP-2058294-A1 | 2-(4-METHOXYCARBONYLMETHYLPHENOXYMETHYL)BENZOIC ACID METHYL ESTER AND METHOD FOR PRODUCING THE SAME | Sumitomo Chemical Company, Limited (JP) | 2009-05-13 | — | — | EP | disclosed |
| WO-2007110761-A2 | POLYMORPHIC FORMS OF OLOPATADINE HYDROCHLORIDE AND METHODS FOR PRODUCING OLOPATADINE AND SALTS THEREOF | Universität Zürich (CH) | 2007-10-04 | — | — | WO | disclosed |
| US-20070232814-A1 | Polymorphic forms of olopatadine hydrochloride and methods for producing olopatadine and salts thereof | UNIVERSITAT ZURICH (CH) | 2007-10-04 | — | — | US | disclosed |
| US-20070232814-A1 | Polymorphic forms of olopatadine hydrochloride and methods for producing olopatadine and salts thereof | UNIVERSITAT ZURICH (CH) | 2007-10-04 | — | — | US | disclosed |
| US-4816591-A | 6,11-dihydrodibenz[b,e]oxepin-acetic acids and derivatives | AMERICAN HOECHST CORPORATION (US) | 1989-03-28 | — | — | US | disclosed |
| US-4585788-A | 6,11-dihydrodibenz[b,e]oxepin-acetic acids and derivatives | AMERICAN HOECHST CORPORATION (US) | 1986-04-29 | — | — | US | disclosed |
| US-4082850-A | TOPICAL APPLICATION OF A 6,11-DIHYDROBENZ(B,E)OXEPIN-ALKANOIC ACID OR DERIVATIVES THEREOF | AMERICAN HOECHST CORPORATION (US) | 1978-04-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070232814-A1 | Polymorphic forms of olopatadine hydrochloride and methods for producing olopatadine and salts thereof | HRH4, HRH1, HRH3 | TSHR 775/4885ALDH1A1 1477/4885HPGD 839/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.