Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB2 known ✓ | P30411 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4347775 | 0.76 | ALDH1A1 (0.55) | ALDH1A1DNM1SMN1; SMN2TDP1THRB | |
| SCHEMBL30406844 | 0.74 | DNM1 (0.41) | ALDH1A1DNM1BDKRB2EPHX1 | |
| Bromide SCHEMBL4770077 | 0.72 | DNM1 (0.43) | ALDH1A1DNM1BDKRB2EPHX1 | |
| SCHEMBL4798734 | 0.72 | ALDH1A1 (0.61) | ALDH1A1SMN1; SMN2TDP1THRBEPHX1 | |
| SCHEMBL3235400 | 0.72 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2TDP1THRB | |
| SCHEMBL2800546 | 0.72 | ALDH1A1 (0.43) | ALDH1A1DNM1SMN1; SMN2TDP1THRB | |
| SCHEMBL3243068 | 0.72 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2TDP1THRB | |
| SCHEMBL3238846 | 0.71 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2TDP1THRBEPHX1 | |
| SCHEMBL31447354 | 0.71 | DNM1 (0.38) | ALDH1A1DNM1SMN1; SMN2BDKRB2EPHX1 | |
| SCHEMBL11769136 | 0.70 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2TDP1EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112011317-B | Stabilizer for controlling fine clay dispersion in shale stratum drilling and preparation method thereof | 中国石油天然气集团有限公司 | 2022-08-02 | — | — | CN | claimed |
| CN-113659128-A | Preparation method and application of polyelectrolyte intercalated manganese dioxide | 兰州大学 | 2021-11-16 | — | — | CN | claimed |
| JP-59145248-A | — | — | None | — | — | JP | disclosed |
| JP-55096959-A | — | — | None | — | — | JP | disclosed |
| CN-112011317-B | Stabilizer for controlling fine clay dispersion in shale stratum drilling and preparation method thereof | 中国石油天然气集团有限公司 | 2022-08-02 | — | — | CN | disclosed |
| CN-113659128-A | Preparation method and application of polyelectrolyte intercalated manganese dioxide | 兰州大学 | 2021-11-16 | — | — | CN | disclosed |
| CN-112011317-A | Stabilizer for controlling fine clay dispersion in shale stratum drilling and preparation method thereof | 中国石油天然气集团有限公司 | 2020-12-01 | — | — | CN | disclosed |
| US-9608546-B2 | Actuator | SEIKO EPSON CORPORATION (JP) | 2017-03-28 | — | — | US | disclosed |
| US-20150214860-A1 | ACTUATOR | SEIKO EPSON CORPORATION (JP) | 2015-07-30 | — | — | US | disclosed |
| US-7867592-B2 | Methods, compositions and devices, including electroosmotic pumps, comprising coated porous surfaces | EKSIGENT TECHNOLOGIES, INC. (US) | 2011-01-11 | — | — | US | disclosed |
| EP-2131952-A1 | METHODS, COMPOSITIONS AND DEVICES, INCLUDING ELECTROOSMOTIC PUMPS, COMPRISING COATED POROUS SURFACES | Eksigent Technologies, LLC (US) | 2009-12-16 | — | — | EP | disclosed |
| EP-0012517-A1 | Electroconductive articles and a method of preparing them | CALGON CORPORATION (US) | 1980-06-25 | — | — | EP | disclosed |
| EP-0012516-A1 | Electroconductive polymer compositions for use in the manufacture of electrographic papers and containing a fluorinated alkylphosphate ester | CALGON CORPORATION (US) | 1980-06-25 | — | — | EP | disclosed |
| US-4168165-A | Electrophotographic photosensitive material suitable for offset printing and lithography and process for production thereof | MITA INDUSTRIAL COMPANY LIMITED (JP) | 1979-09-18 | — | — | US | disclosed |
| US-4150387-A | Alternating current electrostatic recording process | MITA INDUSTRIAL COMPANY LTD. (JP) | 1979-04-17 | — | — | US | disclosed |
| US-4132674-A | Electroconductive coating formulation | CALGON CORPORATION (US) | 1979-01-02 | — | — | US | disclosed |
| US-4125462-A | CATIONIC POLYELECTROLYTE OF POLY(VINYLIMIDAZOLINE) BISULFATE | ROHM AND HAAS COMPANY (US) | 1978-11-14 | — | — | US | disclosed |
| US-4105449-A | BLENDED OLEFIN RESIN; ORGANIC LIGHT-SENSITIZER; PHOTOCONDUCTIVE ZINC OXIDE; GROUP 2A, 2B OR 4B METAL FATTY ACID SALT; SILICONE POLYMER | SEKISUI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1978-08-08 | — | — | US | disclosed |
| US-3956571-A | COATING WITH CATIONIC POLYMERS | KANZAKI PAPER MANUFACTURING CO., LTD. (JA) | 1976-05-11 | — | — | US | disclosed |
| US-3953374-A | PERFLUOROALKYL PHOSPHATE SALT | CALGON CORPORATION (US) | 1976-04-27 | — | — | US | disclosed |