Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNMT1 | P26358 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | APAF1 | O14727 | 2/20 | 0.34 |
| ▸ | TDP2 | O95551 | 2/20 | 0.34 |
| ▸ | NSD2 | O96028 | 2/20 | 0.34 |
| ▸ | HKDC1 | Q2TB90 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | GALK1 | P51570 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.33 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Triaziquone SCHEMBL7720256 | 0.90 | DNMT1 (0.44) | DNMT1HTTTP53MAPTSTAT3 | |
| Triaziquone SCHEMBL5306870 | 0.89 | DNMT1 (0.39) | DNMT1HTTTP53MAPTSTAT3 | |
| Triaziquone SCHEMBL322828 | 0.87 | DNMT1 (0.42) | DNMT1HTTTP53MAPTSTAT3 | |
| Triaziquone SCHEMBL33439 | 0.86 | HTT (0.42) | DNMT1HTTTP53MAPTSTAT3 | |
| Triaziquone SCHEMBL11016638 | 0.86 | DNMT1 (0.37) | DNMT1HTTTP53MAPTSTAT3 | |
| Triaziquone SCHEMBL4612122 | 0.85 | DNMT1 (0.41) | DNMT1HTTTP53MAPTSTAT3 | |
| Triaziquone SCHEMBL610295 | 0.84 | DNMT1 (0.42) | DNMT1HTTTP53MAPTSTAT3 | |
| Triaziquone SCHEMBL1725782 | 0.84 | DNMT1 (0.38) | DNMT1HTTTP53MAPTSTAT3 | |
| Triaziquone SCHEMBL8670330 | 0.84 | DNMT1 (0.36) | DNMT1HTTTP53MAPTSTAT3 | |
| Triaziquone SCHEMBL11428634 | 0.83 | DNMT1 (0.41) | DNMT1HTTTP53MAPTSTAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4874797-A | Oligourea polyols, polyether polyols produced from them and the use of these polyols in the isocyanate polyaddition process | BAYER AKTIENGESELLSCHAFT (DE) | 1989-10-17 | — | — | US | disclosed |