Triaziquone

Triaziquone

SCHEMBL8670330

CC(CN)C(O)(O)O.O=C1C=C(N2CC2)C(=O)C(N2CC2)=C1N1CC1

nearest known ligand 0.36

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
DNMT1 P26358 1/20 0.36
TP53 P04637 1/20 0.34
MAPT P10636 1/20 0.34
STAT3 P40763 1/20 0.34
HTT P42858 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
APAF1 O14727 1/20 0.31
TDP2 O95551 1/20 0.31
NSD2 O96028 1/20 0.31
HKDC1 Q2TB90 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Triaziquone SCHEMBL5306870 0.85 DNMT1 (0.39) DNMT1TP53MAPTSTAT3HTT
Triaziquone SCHEMBL10567262 0.84 DNMT1 (0.40) DNMT1TP53MAPTSTAT3HTT
Triaziquone SCHEMBL322828 0.81 DNMT1 (0.42) DNMT1TP53MAPTSTAT3HTT
Triaziquone SCHEMBL7720256 0.80 DNMT1 (0.44) DNMT1TP53MAPTSTAT3HTT
Triaziquone SCHEMBL108508 0.80 DNMT1 (0.41) DNMT1TP53MAPTSTAT3HTT
Triaziquone SCHEMBL5800741 0.80 DNMT1 (0.41) DNMT1TP53MAPTSTAT3HTT
Triaziquone SCHEMBL3100107 0.80 DNMT1 (0.44) DNMT1TP53MAPTSTAT3HTT
Triaziquone SCHEMBL33439 0.80 HTT (0.42) DNMT1TP53MAPTSTAT3HTT
Triaziquone SCHEMBL8585531 0.80 HTT (0.37) DNMT1TP53MAPTSTAT3HTT
Triaziquone SCHEMBL11583629 0.79 DNMT1 (0.41) DNMT1TP53MAPTSTAT3HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0666076-B1 Water in oil emulsion containing retinol OREAL (FR) 1998-12-23 EP claimed