Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 15/20 | 0.50 |
| ▸ | CA2 | P00918 | 15/20 | 0.50 |
| ▸ | CA12 | O43570 | 9/20 | 0.50 |
| ▸ | CA7 | P43166 | 8/20 | 0.50 |
| ▸ | CA13 | Q8N1Q1 | 6/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.45 |
| ▸ | CA9 | Q16790 | 11/20 | 0.42 |
| ▸ | CA6 | P23280 | 7/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 6/20 | 0.42 |
| ▸ | CA5B | Q9Y2D0 | 6/20 | 0.42 |
| ▸ | CA5A | P35218 | 6/20 | 0.42 |
| ▸ | CA4 | P22748 | 5/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7545831 | 0.85 | ALOX15 (0.46) | CA1CA2CA12CA7CA9 | |
| SCHEMBL28661424 | 0.83 | CA1 (0.42) | CA1CA2CA12CA7CA13 | |
| SCHEMBL9711640 | 0.82 | PTGS2 (0.45) | CA1CA2CA12CA7CA13 | |
| SCHEMBL9345418 | 0.82 | CA2 (0.42) | CA1CA2CA12CA7CA13 | |
| SCHEMBL10806506 | 0.81 | ALDH1A1 (0.52) | CA1CA2CA9CA5ACA4 | |
| SCHEMBL10351662 | 0.81 | PTGS2 (0.44) | CA1CA2CA12CA7CA13 | |
| SCHEMBL14322784 | 0.77 | CA2 (0.45) | CA1CA2CA12CA7CA13 | |
| SCHEMBL11127274 | 0.77 | CA2 (0.41) | CA1CA2CA12CA7CA13 | |
| SCHEMBL30548746 | 0.76 | PTGS2 (0.55) | CA1CA2CA12CA7CA13 | |
| SCHEMBL10350653 | 0.76 | PTGS2 (0.55) | CA1CA2CA12CA7CA13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0132230-B1 | PROCESS FOR THE PREPARATION OF SULFONYL UREA | CIBA-GEIGY AG (CH) | 1988-10-05 | — | — | EP | claimed |
| EP-0132230-A2 | Process for the preparation of sulfonyl urea | CIBA-GEIGY AG (CH) | 1985-01-23 | — | — | EP | claimed |
| EP-2914583-A1 | FLUORINATED BENZENESULFONAMIDES AS INHIBITORS OF CARBONIC ANHYDRASE | Vilnius University (LT) | 2015-09-09 | — | — | EP | disclosed |
| WO-2014062044-A1 | FLUORINATED BENZENESULFONAMIDES AS INHIBITORS OF CARBONIC ANHYDRASE | VILNIUS UNIVERSITY (LT) | 2014-04-24 | — | — | WO | disclosed |
| US-4818277-A | HERBICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-04-04 | — | — | US | disclosed |
| EP-0132230-B1 | PROCESS FOR THE PREPARATION OF SULFONYL UREA | CIBA-GEIGY AG (CH) | 1988-10-05 | — | — | EP | disclosed |
| US-4656273-A | Process for producing sulfonylureas | CIBA-GEIGY CORPORATION (US) | 1987-04-07 | — | — | US | disclosed |
| EP-0132230-A2 | Process for the preparation of sulfonyl urea | CIBA-GEIGY AG (CH) | 1985-01-23 | — | — | EP | disclosed |