Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.58 |
| ▸ | DRD3 | P35462 | 2/20 | 0.53 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.53 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.53 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.53 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.53 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.53 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.53 |
| ▸ | DRD2 | P14416 | 1/20 | 0.53 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.53 |
| ▸ | DRD4 | P21917 | 1/20 | 0.53 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.53 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.53 |
| ▸ | HTR1A | P08908 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10575317 | 0.95 | SIGMAR1 (0.54) | SIGMAR1DRD3ADRB2CHRM2CHRM4 | |
| SCHEMBL10569588 | 0.92 | SIGMAR1 (0.56) | SIGMAR1DRD3DRD2DRD4HTR1A | |
| SCHEMBL10568767 | 0.89 | SIGMAR1 (0.58) | SIGMAR1DRD3ADRB2CHRM2CHRM4 | |
| SCHEMBL10572966 | 0.89 | DRD2 (0.52) | SIGMAR1DRD3DRD2DRD4ADRA1D | |
| SCHEMBL10567416 | 0.86 | SIGMAR1 (0.54) | SIGMAR1DRD3ADRB2CHRM2CHRM4 | |
| SCHEMBL10570155 | 0.85 | HTR1A (0.57) | SIGMAR1DRD3ADRB2CHRM2CHRM4 | |
| SCHEMBL11070274 | 0.84 | CHRM1 (0.55) | SIGMAR1DRD3CHRM2CHRM4CHRM5 | |
| SCHEMBL11062798 | 0.83 | CHRM2 (0.60) | DRD3ADRB2CHRM2CHRM4ADRB1 | |
| SCHEMBL10570390 | 0.83 | MAPT (0.56) | — | |
| Hydrochloric Acid SCHEMBL10570172 | 0.82 | MAPT (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4734416-A | ANTIHISTAMINES, CENTRAL NERVOUS SYSTEM CONTROLLING ACTION | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1988-03-29 | — | — | US | claimed |
| JP-62149664-A | — | — | None | — | — | JP | disclosed |
| US-4824840-A | ANTIHISTAMINES, NERVOUS SYSTEM CONTROLLERS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1989-04-25 | — | — | US | disclosed |
| US-4734416-A | ANTIHISTAMINES, CENTRAL NERVOUS SYSTEM CONTROLLING ACTION | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1988-03-29 | — | — | US | disclosed |
| JP-S62149664-A | PRODUCTION OF CARBOSTYRIL DERIVATIVE | OTSUKA PHARMACEUT CO LTD | 1987-07-03 | — | — | JP | disclosed |