Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.40 |
| ▸ | EED | O75530 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10568102 | 0.87 | MEN1 (0.46) | ALDH1A1KDM4ECYP1A2LMNACA5A | |
| SCHEMBL10567701 | 0.86 | CYP1A2 (0.43) | ALDH1A1KDM4ECYP1A2NOTUMGAA | |
| SCHEMBL2440579 | 0.85 | NOTUM (0.53) | ALDH1A1KDM4ECYP1A2NOTUMGAA | |
| SCHEMBL15956806 | 0.81 | KDM4C (0.52) | ALDH1A1KDM4ECYP1A2NOTUMLMNA | |
| SCHEMBL12179543 | 0.81 | CA5A (0.46) | ALDH1A1KDM4ECA5A | |
| SCHEMBL9248509 | 0.80 | LMNA (0.60) | ALDH1A1CYP1A2NOTUMLMNASMN1; SMN2 | |
| SCHEMBL30587618 | 0.80 | ALDH1A1 (0.47) | ALDH1A1NOTUMLMNASMN1; SMN2HPGD | |
| SCHEMBL9714146 | 0.80 | CA5A (0.58) | CA5A | |
| SCHEMBL9714332 | 0.80 | KLKB1 (0.44) | ALDH1A1LMNACA5A | |
| SCHEMBL10570251 | 0.79 | ALDH1A1 (0.48) | ALDH1A1KDM4ENOTUMLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4851424-A | 1-Phenyl-lower alkyl-imidazole 4- or 5-carboxamide compounds which are useful in the treatment of epilepsy | CIBA-GEIGY CORPORATION (US) | 1989-07-25 | — | — | US | disclosed |