Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.45 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.42 |
| ▸ | CA5A | P35218 | 1/20 | 0.42 |
| ▸ | SCD | O00767 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | JAK1 | P23458 | 1/20 | 0.37 |
| ▸ | JAK3 | P52333 | 1/20 | 0.37 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10568262 | 0.87 | ALDH1A1 (0.48) | CA5AALDH1A1KDM4ELMNAMAPT | |
| SCHEMBL10568691 | 0.85 | KDM5A (0.51) | MEN1KMT2AGRM2CYP2C19ALDH1A1 | |
| SCHEMBL9714265 | 0.84 | RIPK1 (0.42) | RIPK1CA5ASCDCYP2C19JAK2 | |
| SCHEMBL12179543 | 0.83 | CA5A (0.46) | RIPK1CA5AALDH1A1KDM4EKLKB1 | |
| SCHEMBL9714146 | 0.82 | CA5A (0.58) | GRM2RIPK1CA5AJAK2JAK1 | |
| SCHEMBL9714332 | 0.82 | KLKB1 (0.44) | MEN1KMT2ARIPK1CA5ACYP2C19 | |
| SCHEMBL9714339 | 0.82 | RIPK1 (0.41) | MEN1KMT2ARIPK1CA5ASCD | |
| SCHEMBL9714241 | 0.79 | RIPK1 (0.43) | MEN1KMT2ARIPK1CA5ACYP2C19 | |
| SCHEMBL30587512 | 0.79 | GRM2 (0.56) | MEN1KMT2AGRM2SCDKDM4E | |
| SCHEMBL10570402 | 0.79 | GRM2 (0.56) | MEN1KMT2AGRM2SCDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113994970-B | Substituted sulfonamides for combating animal pests | 拜耳公司 | 2023-05-12 | — | — | CN | disclosed |
| CN-113994970-A | Substituted sulfonamides for combating animal pests | 拜耳公司 | 2022-02-01 | — | — | CN | disclosed |
| EP-3534709-B1 | SUBSTITUTED SULFONYLAMIDE FOR COMBATING ANIMAL PESTS | BAYER AG (DE) | 2021-06-16 | — | — | EP | disclosed |
| EP-3534709-B1 | SUBSTITUTED SULFONYLAMIDE FOR COMBATING ANIMAL PESTS | BAYER AG (DE) | 2021-06-16 | — | — | EP | disclosed |
| US-10820591-B2 | Substituted sulfonyl amides for controlling animal pests | BAYER AKTIENGESELLSCHAFT (DE) | 2020-11-03 | — | — | US | disclosed |
| US-10820591-B2 | Substituted sulfonyl amides for controlling animal pests | BAYER AKTIENGESELLSCHAFT (DE) | 2020-11-03 | — | — | US | disclosed |
| EP-3534709-A1 | SUBSTITUTED SULFONYL AMIDES FOR CONTROLLING ANIMAL PESTS | Bayer Aktiengesellschaft (DE) | 2019-09-11 | — | — | EP | disclosed |
| US-20190269134-A1 | SUBSTITUTED SULFONYL AMIDES FOR CONTROLLING ANIMAL PESTS | BAYER AKTIENGESELLSCHAFT (DE) | 2019-09-05 | — | — | US | disclosed |
| US-20190269134-A1 | SUBSTITUTED SULFONYL AMIDES FOR CONTROLLING ANIMAL PESTS | BAYER AKTIENGESELLSCHAFT (DE) | 2019-09-05 | — | — | US | disclosed |
| CN-110191639-A | Substituted sulfonamides for combating animal pests | 拜耳公司 | 2019-08-30 | — | — | CN | disclosed |
| US-4851424-A | 1-Phenyl-lower alkyl-imidazole 4- or 5-carboxamide compounds which are useful in the treatment of epilepsy | CIBA-GEIGY CORPORATION (US) | 1989-07-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190269134-A1 | SUBSTITUTED SULFONYL AMIDES FOR CONTROLLING ANIMAL PESTS | MLYCD, STOM, DDT | MEN1 878/4885KMT2A 380/4885GRM2 283/4885 |
| US-10820591-B2 | Substituted sulfonyl amides for controlling animal pests | MLYCD, STOM, DDT | MEN1 878/4885KMT2A 380/4885GRM2 283/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.