SCHEMBL10568457

SCHEMBL10568457

CCOC(=O)CC(=O)c1ccc(OC)c(C)c1

nearest known ligand 0.64

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.64
KMT2A Q03164 3/20 0.64
ALDH1A1 P00352 2/20 0.64
KDM4E B2RXH2 1/20 0.64
TAS1R3 Q7RTX0 10/20 0.53
TAS1R1 Q7RTX1 10/20 0.53
MAPT P10636 3/20 0.47
HSD17B2 P37059 1/20 0.47
CTNNB1 P35222 1/20 0.47
WNT3A P56704 1/20 0.47
TSHR P16473 1/20 0.47
GAA P10253 2/20 0.46
SMN1; SMN2 Q16637 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2848397 0.89 MEN1 (0.70) MEN1KMT2AALDH1A1KDM4EMAPT
SCHEMBL31314527 0.89 MEN1 (0.70) MEN1KMT2AALDH1A1KDM4EMAPT
SCHEMBL12378894 0.88 MEN1 (0.68) MEN1KMT2AALDH1A1KDM4ETAS1R3
SCHEMBL6085421 0.87 CTNNB1 (0.56) MEN1KMT2AALDH1A1KDM4ETAS1R3
SCHEMBL3189296 0.85 ALDH1A1 (0.61) MEN1KMT2AALDH1A1KDM4ETAS1R3
SCHEMBL31493234 0.85 MEN1 (0.61) MEN1KMT2AALDH1A1KDM4ETAS1R3
SCHEMBL28546622 0.85 ALDH1A1 (0.56) MEN1KMT2AALDH1A1KDM4ETAS1R3
SCHEMBL16273683 0.84 ALDH1A1 (0.49) MEN1KMT2AALDH1A1KDM4ETAS1R3
SCHEMBL30951612 0.84 ALDH1A1 (0.54) MEN1KMT2AALDH1A1KDM4ETAS1R3
SCHEMBL29254490 0.84 ALDH1A1 (0.54) MEN1KMT2AALDH1A1KDM4ETAS1R3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025065102-A1 PHENYLTHIONE-2,3-DIHYDRO-1H-PYRROLIZINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS THEREOF USEFUL AS H2S-RELEASING KETOROLAC ANALOGUES ANTIBE THERAPEUTICS INC. (CA) 2025-04-03 WO disclosed
EP-3130584-B1 AROMATIC COMPOUND AND USES THEREOF SUMITOMO CHEMICAL CO (JP) 2023-04-26 EP disclosed
US-9907307-B2 Aromatic compound and uses thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-03-06 US disclosed
US-9907307-B2 Aromatic compound and uses thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-03-06 US disclosed
US-9828389-B2 Tetrazolinone compounds and their use as pesticides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-11-28 US disclosed
US-9828389-B2 Tetrazolinone compounds and their use as pesticides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-11-28 US disclosed
US-9828389-B2 Tetrazolinone compounds and their use as pesticides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-11-28 US disclosed
EP-2900654-B1 TETRAZOLINONE COMPOUNDS AND THEIR USE AS PESTICIDES SUMITOMO CHEMICAL CO (JP) 2017-05-17 EP disclosed
EP-2900654-B1 TETRAZOLINONE COMPOUNDS AND THEIR USE AS PESTICIDES SUMITOMO CHEMICAL CO (JP) 2017-05-17 EP disclosed
EP-2900655-B1 TETRAZOLINONE COMPOUNDS AND THEIR USE AS PESTICIDES SUMITOMO CHEMICAL CO (JP) 2017-05-10 EP disclosed
EP-2900655-A1 TETRAZOLINONE COMPOUNDS AND THEIR USE AS PESTICIDES SUMITOMO CHEMICAL COMPANY LIMITED (JP) 2015-08-05 EP disclosed
US-20150203511-A1 TETRAZOLINONE COMPOUNDS AND THEIR USE AS PESTICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-07-23 US disclosed
US-20150203511-A1 TETRAZOLINONE COMPOUNDS AND THEIR USE AS PESTICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-07-23 US disclosed
US-20150203511-A1 TETRAZOLINONE COMPOUNDS AND THEIR USE AS PESTICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-07-23 US disclosed
WO-2015050039-A1 PLANT DISEASE CONTROL COMPOSITION AND USE THEREOF 住友化学株式会社 2015-04-09 WO disclosed
WO-2015050040-A1 PLANT DISEASE CONTROL COMPOSITION AND USE THEREOF 住友化学株式会社 2015-04-09 WO disclosed
US-4824851-A Pyrimidones as cardiotonic, anti hypertensive, cerebrovascular vasodilator and anti-platelet agents FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1989-04-25 US disclosed
EP-0123402-B1 PYRIMIDINE DERIVATIVES, PREPARATION THEREOF AND USE THEREOF FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1988-09-07 EP disclosed
US-4746664-A Substituted-3,4-dihydro-4-(2,4,6-trimethoxyphenylimino)-2(1H)-pyrimidones useful as cardiotonic, antihypertensive, cerebrovascular vasodilator and anti-platelet agent FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1988-05-24 US disclosed
EP-0123402-A2 Pyrimidine derivatives, preparation thereof and use thereof FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1984-10-31 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150203511-A1 TETRAZOLINONE COMPOUNDS AND THEIR USE AS PESTICIDES CYCS, MT-CO3, CYP4F11 MEN1 2120/4885KMT2A 2735/4885ALDH1A1 1436/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.