SCHEMBL2848397

SCHEMBL2848397

CCOC(=O)CC(=O)c1ccc(OC)c(OC)c1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.70
KMT2A Q03164 5/20 0.70
ALDH1A1 P00352 4/20 0.70
KDM4E B2RXH2 1/20 0.70
MAPT P10636 4/20 0.59
TSHR P16473 3/20 0.59
CTNNB1 P35222 2/20 0.59
WNT3A P56704 2/20 0.59
GAA P10253 2/20 0.56
SMN1; SMN2 Q16637 1/20 0.56
MAPK1 P28482 1/20 0.55
CYP2C19 P33261 2/20 0.55
POLB P06746 1/20 0.55
CYP1A2 P05177 1/20 0.54
CYP3A4 P08684 1/20 0.54
CYP2C9 P11712 1/20 0.54
CA12 O43570 1/20 0.53
CA1 P00915 1/20 0.53
CA2 P00918 1/20 0.53
CA4 P22748 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31314527 1.00 MEN1 (0.70) MEN1KMT2AALDH1A1KDM4EMAPT
SCHEMBL10568457 0.89 MEN1 (0.64) MEN1KMT2AALDH1A1KDM4EMAPT
SCHEMBL12378894 0.89 MEN1 (0.68) MEN1KMT2AALDH1A1KDM4EMAPT
SCHEMBL25966580 0.88 HSD17B2 (0.68) MEN1KMT2AALDH1A1KDM4EMAPT
SCHEMBL7380780 0.87 MAPT (0.61) MEN1KMT2AALDH1A1MAPTTSHR
SCHEMBL15657696 0.87 ALDH1A1 (0.65) MEN1KMT2AALDH1A1KDM4EMAPT
SCHEMBL3189296 0.87 ALDH1A1 (0.61) MEN1KMT2AALDH1A1KDM4EMAPT
SCHEMBL31493234 0.87 MEN1 (0.61) MEN1KMT2AALDH1A1KDM4EMAPT
SCHEMBL15657764 0.87 MEN1 (0.65) MEN1KMT2AALDH1A1KDM4EMAPT
SCHEMBL11705162 0.86 CTNNB1 (0.70) MEN1KMT2AALDH1A1KDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 169 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026087561-A1 RETARDING AGENT IN ISOCYANATE COMPONENT OF POLYURETHANE/UREA CEMENTITIOUS HYBRID SYSTEMS SIKA TECHNOLOGY AG (CH) 2026-04-30 WO claimed
EP-4733284-A1 RETARDING AGENT IN ISOCYANATE COMPONENT OF POLYURETHANE/UREA CEMENTITIOUS HYBRID SYSTEMS Sika Technology AG (CH) 2026-04-29 EP claimed
EP-4063422-A1 1,3-DICARBONYL COMPOUNDS AS RETARDING ADDITIVES FOR UCRETE SYSTEMS Construction Research & Technology GmbH (DE) 2022-09-28 EP claimed
CN-109369592-A A kind of synthetic method of sweet orange flavones 陕西嘉禾生物科技股份有限公司 2019-02-22 CN claimed
US-9422583-B2 Stereospecific carbonyl reductases RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2016-08-23 US claimed
US-20150167032-A1 STEREOSPECIFIC CARBONYL REDUCTASES JIANGNAN UNIVERSITY (CN) 2015-06-18 US claimed
CN-102482649-B Stereospecific carbonyl reductases UNIV RUTGERS 2014-09-03 CN claimed
US-20120270285-A1 STEREOSPECIFIC CARBONYL REDUCTASES RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY 2012-10-25 US claimed
CN-102482649-A Stereospecific carbonyl reductases UNIV RUTGERS 2012-05-30 CN claimed
WO-2010151593-A1 STEROSPECIFIC CARBONYL REDUCTASES RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2010-12-29 WO claimed
CN-1297552-C Process for synthesizing luteolin NANJING RALLY BIOCHEMICAL CO L (CN) 2007-01-31 CN claimed
WO-2026087561-A1 RETARDING AGENT IN ISOCYANATE COMPONENT OF POLYURETHANE/UREA CEMENTITIOUS HYBRID SYSTEMS SIKA TECHNOLOGY AG (CH) 2026-04-30 WO disclosed
EP-4733284-A1 RETARDING AGENT IN ISOCYANATE COMPONENT OF POLYURETHANE/UREA CEMENTITIOUS HYBRID SYSTEMS Sika Technology AG (CH) 2026-04-29 EP disclosed
US-11964985-B2 Anti-cancer compounds targeting Ral GTPases and methods of using the same The Regents of the University of Colorado, a body corporate. (US) 2024-04-23 US disclosed
US-20240067646-A1 COMPOUNDS FOR TREATING SPINAL MUSCULAR ATROPHY HOFFMANN-LA ROCHE INC. 2024-02-29 US disclosed
EP-0101330-B1 2-QUINOLONE DERIVATIVES NIPPON SHINYAKU COMPANY, LIMITED (JP) 1988-08-24 EP disclosed
US-4727073-A CEREBOVASCULAR DISEASES FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1988-02-23 US disclosed
EP-0177287-A2 Pyrimidine derivatives, processes for preparation thereof and composition of the same FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1986-04-09 EP disclosed
US-4526894-A Antiinflammatory agents NIPPON SHINYAKU CO. LTD. (JP) 1985-07-02 US disclosed
EP-0101330-A2 2-Quinolone derivatives NIPPON SHINYAKU COMPANY, LIMITED (JP) 1984-02-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240067646-A1 COMPOUNDS FOR TREATING SPINAL MUSCULAR ATROPHY SMN1; SMN2, CPT1B, GYS1 MEN1 3423/4885KMT2A 1582/4885ALDH1A1 1088/4885
US-11964985-B2 Anti-cancer compounds targeting Ral GTPases and methods of using the same ARFGAP1, ARHGDIB, IQGAP1 MEN1 1827/4885KMT2A 2921/4885ALDH1A1 3045/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.