Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.68 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.50 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.50 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.47 |
| ▸ | WNT3A | P56704 | 2/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | STAT3 | P40763 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31314527 | 0.89 | MEN1 (0.70) | MEN1KMT2AALDH1A1KDM4EHSD17B2 | |
| SCHEMBL2848397 | 0.89 | MEN1 (0.70) | MEN1KMT2AALDH1A1KDM4EHSD17B2 | |
| SCHEMBL10568457 | 0.88 | MEN1 (0.64) | MEN1KMT2AALDH1A1KDM4EHSD17B2 | |
| SCHEMBL25966580 | 0.87 | HSD17B2 (0.68) | MEN1KMT2AALDH1A1KDM4EHSD17B2 | |
| SCHEMBL15657764 | 0.85 | MEN1 (0.65) | MEN1KMT2AALDH1A1KDM4EHSD17B2 | |
| SCHEMBL15657696 | 0.85 | ALDH1A1 (0.65) | MEN1KMT2AALDH1A1KDM4EHSD17B2 | |
| SCHEMBL28550369 | 0.85 | ALDH1A1 (0.56) | MEN1KMT2AALDH1A1KDM4EHSD17B2 | |
| SCHEMBL31320787 | 0.85 | ALDH1A1 (0.56) | MEN1KMT2AALDH1A1KDM4EHSD17B2 | |
| SCHEMBL7434555 | 0.84 | KMT2A (0.63) | MEN1KMT2AALDH1A1KDM4EHSD17B2 | |
| SCHEMBL30951612 | 0.84 | ALDH1A1 (0.54) | MEN1KMT2AALDH1A1KDM4ETAS1R3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110190514-A1 | PYRONE ANALOG COMPOSITIONS AND METHODS | LIMERICK BIOPHARMA, INC. (US) | 2011-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110190514-A1 | PYRONE ANALOG COMPOSITIONS AND METHODS | CYP11B2, CYP11B1, GLS2 | MEN1 535/4885KMT2A 4673/4885ALDH1A1 3621/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.