SCHEMBL10568478

SCHEMBL10568478

NC(=O)N(C(N)=S)C(N)=S

nearest known ligand 0.33

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.33
ATM Q13315 1/20 0.33
ATR Q13535 1/20 0.33
ALDH1A1 P00352 1/20 0.33
LMNA P02545 1/20 0.33
OR51E2 Q9H255 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
ACHE P22303 1/20 0.31
TAS2R38 P59533 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL398414 0.93 TSHR (0.33) TSHRATMATRALDH1A1LMNA
SCHEMBL3056862 0.76 LMNA (0.46) TSHRALDH1A1LMNAOR51E2TDP1
SCHEMBL6271059 0.73 LMNA (0.41) LMNATDP1TAS2R38
SCHEMBL27501238 0.69
SCHEMBL11523090 0.67 ACHE (0.43) ALDH1A1LMNAOR51E2TDP1ACHE
SCHEMBL23464774 0.65
SCHEMBL27515848 0.65
SCHEMBL5799121 0.64 ALDH1A1 (0.33) ALDH1A1LMNAOR51E2TDP1ACHE
SCHEMBL1696462 0.64 LMNA (0.47) TSHRALDH1A1LMNAOR51E2TDP1
SCHEMBL11501793 0.64 ALDH1A1 (0.33) ALDH1A1LMNAOR51E2TDP1ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0154437-B1 SUBSTITUTED DITHIOCARBAMYLUREA ACCELERATORS UNIROYAL CHEMICAL COMPANY, Inc. (US) 1989-06-14 EP disclosed
EP-0154437-B1 SUBSTITUTED DITHIOCARBAMYLUREA ACCELERATORS UNIROYAL CHEMICAL COMPANY, Inc. (US) 1989-06-14 EP disclosed
US-4808714-A SULFUR CURE ACCELERATORS WITH IMPROVED SCORCH SAFETY UNIROYAL CHEMICAL COMPANY, INC. (US) 1989-02-28 US disclosed
US-4808714-A SULFUR CURE ACCELERATORS WITH IMPROVED SCORCH SAFETY UNIROYAL CHEMICAL COMPANY, INC. (US) 1989-02-28 US disclosed
US-4808714-A SULFUR CURE ACCELERATORS WITH IMPROVED SCORCH SAFETY UNIROYAL CHEMICAL COMPANY, INC. (US) 1989-02-28 US disclosed
US-4631316-A Curable rubber compositions comprising substituted dithiocarbamylurea accelerators UNIROYAL CHEMICAL COMPANY, INC. (US) 1986-12-23 US disclosed
US-4631316-A Curable rubber compositions comprising substituted dithiocarbamylurea accelerators UNIROYAL CHEMICAL COMPANY, INC. (US) 1986-12-23 US disclosed
EP-0154437-A2 Substituted dithiocarbamylurea accelerators UNIROYAL CHEMICAL COMPANY, Inc. (US) 1985-09-11 EP disclosed
EP-0154437-A2 Substituted dithiocarbamylurea accelerators UNIROYAL CHEMICAL COMPANY, Inc. (US) 1985-09-11 EP disclosed