SCHEMBL5799121

SCHEMBL5799121

N=C(N)N(C(=N)N)C(N)=O

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.33
LMNA P02545 1/20 0.33
OR51E2 Q9H255 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
ACHE P22303 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11501793 0.93 ALDH1A1 (0.33) ALDH1A1LMNAOR51E2TDP1ACHE
SCHEMBL3073845 0.87
SCHEMBL6263757 0.84 NOS3 (0.33)
Nitric Acid SCHEMBL6267090 0.84 CA5A (0.40)
SCHEMBL3062852 0.80
SCHEMBL3070671 0.80
SCHEMBL28022214 0.76 MAPK1 (0.31)
SCHEMBL3056862 0.76 LMNA (0.46) ALDH1A1LMNAOR51E2TDP1ACHE
SCHEMBL28405955 0.76 ACHE (0.38) ALDH1A1LMNAOR51E2TDP1ACHE
SCHEMBL11801856 0.73 LDHA (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-53059626-A None JP disclosed
WO-2021113623-A1 CHEMICAL ACTIVATION OF SELF-PASSIVATING METALS SWAGELOK COMPANY (US) 2021-06-10 WO disclosed
CN-1321157-C Modifier for thermoplastic resin and thermoplastic resin composition containing the same MITSUBISHI RAYON CO (JP) 2007-06-13 CN disclosed
CN-1301939-C Burn rate enhancement via a transition metal complex of diammonium bitetrazole AUTOLIV ASP INC (US) 2007-02-28 CN disclosed
US-20060096679-A1 Burn rate enhancement of basic copper nitrate-containing gas generant compositions AUTOLIV ASP, INC. 2006-05-11 US disclosed
WO-2006047085-A2 BURN RATE ENHANCEMENT OF BASIC COPPER NITRATE-CONTAINING GAS GENERANT COMPOSITIONS AUTOLIV ASP, INC. (US) 2006-05-04 WO disclosed
US-6849733-B1 Neuropeptide-Y ligands AGOURON PHARMACEUTICALS, INC. (US) 2005-02-01 US disclosed
CN-1507470-A Modifier for thermoplastic resin and thermoplastic resin composition using same 三菱丽阳株式会社 2004-06-23 CN disclosed
EP-0984778-B1 NEUROPEPTIDE-Y LIGANDS AGOURON PHARMA (US) 2002-06-12 EP disclosed
EP-0984778-A4 NEUROPEPTIDE-Y LIGANDS ALANEX CORP (US) 2000-06-07 EP disclosed
EP-0984778-A1 NEUROPEPTIDE-Y LIGANDS Alanex Corporation (US) 2000-03-15 EP disclosed
WO-1998007420-A1 NEUROPEPTIDE-Y LIGANDS AGOURON ACQUISITION CORP. (US) 1998-02-26 WO disclosed
US-4209624-A Process for preparing substituted bis(amidinoureas) COOPER LABORATORIES, INC. (US) 1980-06-24 US disclosed
JP-S5359626-A PROCESS FOR MANUFACTURING SUBSTITUTED BIS*AMIDINO UREA* COOPER LAB 1978-05-29 JP disclosed