Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPM1B | O75688 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9675417 | 0.85 | SMN1; SMN2 (0.41) | PPM1BPTPN1PPP1CCGAASMN1; SMN2 | |
| SCHEMBL9675194 | 0.74 | CYP1A2 (0.32) | PPM1BPTPN1PPP1CC | |
| SCHEMBL9675102 | 0.72 | CYP1A2 (0.34) | PPM1BPTPN1PPP1CC | |
| SCHEMBL17674468 | 0.69 | ALDH1A1 (0.34) | GAASMN1; SMN2 | |
| SCHEMBL16086418 | 0.66 | HCAR2 (0.39) | PPM1BPTPN1PPP1CCESR1 | |
| SCHEMBL294867 | 0.66 | PPM1B (0.42) | PPM1BPTPN1PPP1CCESR1ESR2 | |
| SCHEMBL6078331 | 0.65 | LMNA (0.38) | GAASMN1; SMN2 | |
| SCHEMBL25885236 | 0.64 | PPM1B (0.45) | PPM1BPTPN1PPP1CC | |
| SCHEMBL16671106 | 0.64 | MAPT (0.38) | PPM1BPTPN1PPP1CC | |
| SCHEMBL294366 | 0.63 | PPM1B (0.47) | PPM1BPTPN1PPP1CC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4874872-A | Process for preparing (+)-2,3-dihydro-1H-pyrrolo[1,2-A]pyrrole-1,7-dicarboxylates | SYNTEX (U.S.A.) INC. (US) | 1989-10-17 | — | — | US | disclosed |
| US-4849526-A | Process for preparing (±)-2,3-dihydro-1H-pyrrolo[1,2-A]pyrrole-1,7-dicarboxylates | SYNTEX (U.S.A.) INC. (US) | 1989-07-18 | — | — | US | disclosed |