Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 4/20 | 0.44 |
| ▸ | PPARD | Q03181 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9862607 | 0.90 | FFAR1 (0.42) | RORCPPARD | |
| SCHEMBL10449740 | 0.86 | SIGMAR1 (0.41) | LMNA | |
| SCHEMBL5854536 | 0.82 | PTGFR (0.38) | RORCPPARDPDE4B | |
| SCHEMBL5854254 | 0.82 | PTGFR (0.38) | RORCPPARDPDE4B | |
| SCHEMBL9635181 | 0.82 | SIGMAR1 (0.40) | LMNAMAPTHSD17B1RECQLSMN1; SMN2 | |
| SCHEMBL9634372 | 0.82 | SIGMAR1 (0.39) | LMNAMAPTHSD17B1RECQLSMN1; SMN2 | |
| SCHEMBL10918844 | 0.81 | MTNR1A (0.41) | — | |
| SCHEMBL9862665 | 0.80 | LMNA (0.42) | PPARDLMNAMAPTHSD17B1RECQL | |
| SCHEMBL5853638 | 0.78 | PTGFR (0.35) | RORCPPARDMAPTPDE4B | |
| SCHEMBL10594963 | 0.76 | ESR1 (0.38) | PPARDLMNAMAPTHSD17B1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4833135-A | Antioestrogenic phenol derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1989-05-23 | — | — | US | disclosed |