Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10565721 | 0.90 | ALDH1A1 (0.43) | ALDH1A1GAATP53KDM4EGLA | |
| SCHEMBL10568945 | 0.87 | ALDH1A1 (0.51) | ALDH1A1GAATP53KDM4EGLA | |
| SCHEMBL10569039 | 0.86 | ALDH1A1 (0.50) | ALDH1A1GAATP53KDM4EGLA | |
| SCHEMBL10568464 | 0.85 | TSHR (0.41) | ALDH1A1GAATP53KDM4EGLA | |
| SCHEMBL10570474 | 0.83 | CRHBP (0.43) | ALDH1A1GAAPOLBMAPTMEN1 | |
| SCHEMBL10567844 | 0.82 | AADAT (0.41) | ALDH1A1GAAPOLBMAPTMEN1 | |
| SCHEMBL10570442 | 0.79 | ALDH1A1 (0.44) | ALDH1A1GAATP53KDM4EGLA | |
| SCHEMBL16450870 | 0.78 | ALDH1A1 (0.55) | ALDH1A1GAATP53KDM4EGLA | |
| SCHEMBL10569629 | 0.76 | HTR7 (0.45) | ALDH1A1GAAPOLBMAPTMEN1 | |
| SCHEMBL10573727 | 0.75 | ALDH1A1 (0.62) | ALDH1A1GAAHPGDHTTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4847285-A | 1-substituted phenyl-3-substituted methyl-pyrrolidine-2,5-diones and plant fungicide compositions containing same | THE DOW CHEMICAL COMPANY (US) | 1989-07-11 | — | — | US | disclosed |
| EP-0173284-A1 | Substituted 1-phenyl-3-methyl-pyrrolidindiones, their manufacture and use as fungicides | THE DOW CHEMICAL COMPANY (US) | 1986-03-05 | — | — | EP | disclosed |