Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.35 |
| ▸ | TAB1 | Q15750 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | G6PD | P11413 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29178655 | 0.79 | ALDH1A1 (0.39) | ADORA2AMAP3K7TAB1ALDH1A1MAPT | |
| SCHEMBL10569355 | 0.71 | ALDH1A1 (0.45) | ADORA2AMAP3K7TAB1ALDH1A1MAPT | |
| SCHEMBL10188533 | 0.69 | GSK3A (0.39) | MAP3K7TAB1ALDH1A1MAPTKDM4E | |
| SCHEMBL29178712 | 0.68 | — | — | |
| SCHEMBL30953676 | 0.66 | L3MBTL1 (0.50) | MAP3K7TAB1ALDH1A1MAPTKDM4E | |
| SCHEMBL25244784 | 0.64 | MAPT (0.39) | ADORA2AMAP3K7TAB1ALDH1A1MAPT | |
| SCHEMBL938838 | 0.64 | HPGD (0.43) | MAPTKDM4EMEN1KMT2A | |
| SCHEMBL9741538 | 0.64 | MAP3K7 (0.37) | MAP3K7TAB1ALDH1A1MAPTKDM4E | |
| SCHEMBL9741879 | 0.64 | MAP3K7 (0.40) | ADORA2AMAP3K7TAB1ALDH1A1MAPT | |
| SCHEMBL23978006 | 0.63 | MAP3K7 (0.34) | MAP3K7TAB1ALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117466897-A | Highly selective FGFR2 inhibitors | 深圳福沃药业有限公司 | 2024-01-30 | — | — | CN | disclosed |