Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 4/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.46 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10564954 | 0.86 | CYP11B2 (0.48) | CYP11B2GABRA1GABRB2CYP11B1CYP1A2 | |
| SCHEMBL9714409 | 0.81 | AURKA (0.40) | LMNA | |
| SCHEMBL16380792 | 0.77 | CYP11B1 (0.57) | CYP11B2GABRA1GABRB2CYP11B1CYP1A2 | |
| SCHEMBL2438549 | 0.77 | CYP11B2 (0.48) | CYP11B2GABRA1GABRB2CYP11B1CYP1A2 | |
| SCHEMBL898835 | 0.76 | GABRA1 (0.50) | CYP11B2GABRA1GABRB2CYP11B1CYP1A2 | |
| SCHEMBL24793268 | 0.74 | GABRA1 (0.52) | CYP11B2GABRA1GABRB2CYP11B1CYP1A2 | |
| SCHEMBL10771365 | 0.74 | ALKBH1 (0.40) | CYP11B2CYP11B1LMNAGAA | |
| SCHEMBL10567701 | 0.74 | CYP1A2 (0.43) | GABRB2CYP1A2LMNAGABRA2ALDH1A1 | |
| SCHEMBL14476466 | 0.73 | CYP11B2 (0.54) | CYP11B2GABRA1GABRB2CYP11B1CYP1A2 | |
| SCHEMBL15652817 | 0.73 | CYP11B1 (0.54) | CYP11B2GABRA1GABRB2CYP11B1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4851424-A | 1-Phenyl-lower alkyl-imidazole 4- or 5-carboxamide compounds which are useful in the treatment of epilepsy | CIBA-GEIGY CORPORATION (US) | 1989-07-25 | — | — | US | disclosed |