Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.45 |
| ▸ | MEN1 | O00255 | 7/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | TDO2 | P48775 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7292014 | 0.88 | KMT2A (0.41) | MAPTKMT2AMEN1GAANPSR1 | |
| SCHEMBL7294604 | 0.87 | PDE4A (0.39) | MAPTKMT2AMEN1GAANPSR1 | |
| SCHEMBL7292065 | 0.86 | HTT (0.37) | MAPTKMT2AMEN1GAAKDM4E | |
| SCHEMBL7291459 | 0.86 | CNR2 (0.36) | MAPTSMN1; SMN2 | |
| SCHEMBL7289330 | 0.85 | MIF (0.34) | KDM4EPOLB | |
| SCHEMBL7287387 | 0.85 | GAA (0.34) | MAPTKMT2AMEN1GAAL3MBTL1 | |
| SCHEMBL10569584 | 0.85 | KDM4E (0.38) | MAPTKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL7286210 | 0.85 | GABRP (0.41) | MAPTKMT2AMEN1NPSR1L3MBTL1 | |
| SCHEMBL7286216 | 0.82 | IDO1 (0.34) | MAPTPOLBIDO1TDO2HSP90AA1 | |
| SCHEMBL7290542 | 0.82 | MAPT (0.41) | MAPTKMT2AMEN1GAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4849421-A | SIDE EFFECT REDUCTION | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1989-07-18 | — | — | US | disclosed |