Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.41 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | MYH2 | Q9UKX2 | 1/20 | 0.35 |
| ▸ | G6PD | P11413 | 1/20 | 0.35 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.35 |
| ▸ | PHOSPHO1 | Q8TCT1 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10570971 | 0.88 | MAPT (0.45) | KMT2AMEN1MAPTGAANPSR1 | |
| SCHEMBL7290530 | 0.83 | PDE4A (0.38) | KMT2AMEN1MAPTGAAL3MBTL1 | |
| SCHEMBL7294604 | 0.83 | PDE4A (0.39) | KMT2AMEN1MAPTGAANPSR1 | |
| SCHEMBL10366069 | 0.82 | MAPT (0.43) | KMT2AMEN1MAPTGAANPSR1 | |
| SCHEMBL10563420 | 0.80 | AMY1A (0.39) | KMT2AMEN1MAPTGAANPSR1 | |
| SCHEMBL10567372 | 0.78 | MEN1 (0.44) | KMT2AMEN1MAPTGAAL3MBTL1 | |
| SCHEMBL10570570 | 0.78 | KDM4E (0.37) | KMT2AMEN1MAPTGAANPSR1 | |
| SCHEMBL7297343 | 0.78 | CNR2 (0.34) | KMT2AMEN1GAAALDH1A1KDM4E | |
| SCHEMBL7286803 | 0.77 | VHL (0.42) | KMT2AMEN1MAPTGAANPSR1 | |
| SCHEMBL10562379 | 0.76 | POLB (0.40) | KMT2AMEN1MAPTGAANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4849421-A | SIDE EFFECT REDUCTION | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1989-07-18 | — | — | US | disclosed |
| EP-0281045-A1 | Benzothiepino (5,4-c) pyridazine compounds and their pharmaceutical uses | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1988-09-07 | — | — | EP | disclosed |