Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 19/20 | 0.95 |
| ▸ | DRD3 | P35462 | 10/20 | 0.93 |
| ▸ | DRD4 | P21917 | 9/20 | 0.93 |
| ▸ | HTR1A | P08908 | 1/20 | 0.69 |
| ▸ | DRD1 | P21728 | 1/20 | 0.69 |
| ▸ | DRD5 | P21918 | 1/20 | 0.69 |
| ▸ | HTR2A | P28223 | 1/20 | 0.69 |
| ▸ | HTR2C | P28335 | 1/20 | 0.69 |
| ▸ | HTR2B | P41595 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL251472 | 0.97 | DRD2 (1.00) | DRD2DRD3DRD4HTR1ADRD1 | |
| SCHEMBL10570451 | 0.96 | DRD2 (1.00) | DRD2DRD3DRD4 | |
| SCHEMBL252295 | 0.94 | DRD2 (1.00) | DRD2DRD3DRD4 | |
| SCHEMBL14974690 | 0.93 | DRD2 (1.00) | DRD2DRD3DRD4 | |
| SCHEMBL11333597 | 0.90 | DRD2 (0.88) | DRD2DRD3DRD4HTR1AHTR2A | |
| SCHEMBL250675 | 0.90 | DRD2 (1.00) | DRD2DRD3DRD4HTR1ADRD1 | |
| SCHEMBL10573201 | 0.88 | DRD2 (0.95) | DRD2DRD3DRD4 | |
| SCHEMBL252031 | 0.88 | DRD2 (1.00) | DRD2DRD3DRD4HTR1ADRD1 | |
| SCHEMBL8078 | 0.86 | DRD2 (1.00) | DRD2DRD3DRD4 | |
| SCHEMBL10569233 | 0.85 | DRD2 (0.87) | DRD2DRD3DRD4HTR1ADRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4824840-A | ANTIHISTAMINES, NERVOUS SYSTEM CONTROLLERS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1989-04-25 | — | — | US | disclosed |
| US-4734416-A | ANTIHISTAMINES, CENTRAL NERVOUS SYSTEM CONTROLLING ACTION | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1988-03-29 | — | — | US | disclosed |