Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 20/20 | 1.00 |
| ▸ | DRD4 | P21917 | 8/20 | 0.85 |
| ▸ | DRD3 | P35462 | 8/20 | 0.85 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10573201 | 0.97 | DRD2 (0.95) | DRD2DRD4DRD3 | |
| SCHEMBL250675 | 0.97 | DRD2 (1.00) | DRD2DRD4DRD3 | |
| SCHEMBL252295 | 0.92 | DRD2 (1.00) | DRD2DRD4DRD3 | |
| SCHEMBL14974690 | 0.91 | DRD2 (1.00) | DRD2DRD4DRD3 | |
| SCHEMBL3157625 | 0.90 | DRD2 (0.81) | DRD2DRD4DRD3 | |
| SCHEMBL3163009 | 0.89 | DRD2 (0.80) | DRD2DRD4DRD3 | |
| Hydrochloric Acid SCHEMBL3153054 | 0.89 | DRD2 (0.80) | DRD2DRD4DRD3 | |
| SCHEMBL10570451 | 0.89 | DRD2 (1.00) | DRD2DRD4DRD3 | |
| Hydrochloric Acid SCHEMBL3154859 | 0.89 | DRD2 (0.79) | DRD2DRD4DRD3 | |
| SCHEMBL251472 | 0.89 | DRD2 (1.00) | DRD2DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0367141-B1 | Carbostyril derivatives | OTSUKA PHARMA CO LTD (JP) | 1996-01-10 | — | — | EP | claimed |
| US-5006528-A | Carbostyril derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-04-09 | — | — | US | claimed |
| EP-0367141-A2 | Carbostyril derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1990-05-09 | — | — | EP | claimed |
| JP-10045718-A | — | — | None | — | — | JP | disclosed |
| US-20130289024-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF FILOVIRUS-MEDIATED DISEASES | U.S. ARMY MEDICAL RESEARCH AND MATERIEL COMMAND | 2013-10-31 | — | — | US | disclosed |
| US-8475804-B2 | Compositions and methods for treatment of filovirus-mediated diseases | U.S. ARMY MEDICAL RESEARCH AND MATERIAL COMMAND (US) | 2013-07-02 | — | — | US | disclosed |
| US-20110028564-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF FILOVIRUS-MEDIATED DISEASES | ZALICUS INC. | 2011-02-03 | — | — | US | disclosed |
| US-20100009983-A1 | 5 HT RECEPTOR MEDIATED NEUROGENESIS | BRAINCELLS, INC. (US) | 2010-01-14 | — | — | US | disclosed |
| US-20100009983-A1 | 5 HT RECEPTOR MEDIATED NEUROGENESIS | BRAINCELLS, INC. (US) | 2010-01-14 | — | — | US | disclosed |
| JP-H1045718-A | CARBOSTYRIL DERIVATIVE | OTSUKA PHARMACEUT CO LTD | 1998-02-17 | — | — | JP | disclosed |
| EP-0367141-B1 | Carbostyril derivatives | OTSUKA PHARMA CO LTD (JP) | 1996-01-10 | — | — | EP | disclosed |
| US-5006528-A | Carbostyril derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-04-09 | — | — | US | disclosed |
| EP-0367141-A2 | Carbostyril derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1990-05-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100009983-A1 | 5 HT RECEPTOR MEDIATED NEUROGENESIS | HTR6, GAP43, HTR5A | DRD2 242/4885DRD4 301/4885DRD3 432/4885 |
| US-20110028564-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF FILOVIRUS-MEDIATED DISEASES | FLNA, FLNB, PIGS | DRD2 4871/4885DRD4 4834/4885DRD3 4854/4885 |
| US-20130289024-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF FILOVIRUS-MEDIATED DISEASES | FLNA, FLNB, PIGS | DRD2 4871/4885DRD4 4834/4885DRD3 4854/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.