Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 6/20 | 0.39 |
| ▸ | AGXT | P21549 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | PER2 | O15055 | 1/20 | 0.32 |
| ▸ | CRY1 | Q16526 | 1/20 | 0.32 |
| ▸ | CRY2 | Q49AN0 | 1/20 | 0.32 |
| ▸ | NAAA | Q02083 | 1/20 | 0.32 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL500057 | 0.82 | IDO1 (0.37) | IDO1AGXTPKMP2RX7MAOB | |
| SCHEMBL19859281 | 0.81 | IDO1 (0.41) | IDO1AGXTPKMP2RX7ALDH1A1 | |
| SCHEMBL12874169 | 0.81 | IDO1 (0.60) | IDO1AGXTSLC6A2SLC6A4KDM4E | |
| SCHEMBL30280664 | 0.80 | PKM (0.41) | PKMP2RX7KDM4EALDH1A1LMNA | |
| SCHEMBL12887513 | 0.79 | MMP1 (0.41) | IDO1AGXTSLC6A2SLC6A4P2RX7 | |
| SCHEMBL5424200 | 0.79 | SLC6A2 (0.36) | IDO1AGXTPKMSLC6A2SLC6A4 | |
| SCHEMBL3711398 | 0.78 | PKM (0.42) | IDO1AGXTPKMP2RX7KDM4E | |
| SCHEMBL30005666 | 0.78 | PKM (0.42) | IDO1AGXTPKMP2RX7KDM4E | |
| SCHEMBL10572077 | 0.78 | L3MBTL1 (0.45) | IDO1AGXTSLC6A2SLC6A4ALDH1A1 | |
| SCHEMBL30280535 | 0.76 | PKM (0.58) | IDO1AGXTPKMP2RX7ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4846882-A | HALOBENZYL DERIVATIVES | FMC CORPORATION (US) | 1989-07-11 | — | — | US | disclosed |
| WO-1987004049-A1 | N-SUBSTITUTED TETRAHYDROPHTHALIMIDE HERBICIDAL COMPOUNDS AND INTERMEDIATES THEREFOR | FMC CORPORATION (US) | 1987-07-16 | — | — | WO | disclosed |