Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | F2R | P25116 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
| ▸ | AGXT | P21549 | 2/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | PARK7 | Q99497 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3711398 | 1.00 | PKM (0.42) | PKMP2RX7GABRA1GABRB2F2R | |
| SCHEMBL7363929 | 0.84 | F2R (0.47) | PKMP2RX7F2RKMT2AMEN1 | |
| SCHEMBL17979961 | 0.83 | LMNA (0.37) | PKMP2RX7F2RMAPTSMN1; SMN2 | |
| SCHEMBL322033 | 0.82 | GABRA1 (0.39) | PKMGABRA1GABRB2F2RKMT2A | |
| SCHEMBL15351654 | 0.82 | PKM (0.42) | PKMP2RX7KMT2AMEN1MAPT | |
| SCHEMBL7363932 | 0.82 | PTPN1 (0.64) | PKMMAPTKDM4ELMNATP53 | |
| SCHEMBL3635959 | 0.79 | TYR (0.47) | P2RX7KMT2AMEN1MAPTTP53 | |
| SCHEMBL1208710 | 0.79 | PKM (0.39) | PKMP2RX7KMT2AMEN1MAPT | |
| SCHEMBL29494112 | 0.79 | PKM (0.39) | PKMP2RX7KMT2AMEN1MAPT | |
| SCHEMBL3667517 | 0.78 | IDO1 (0.40) | PKMMAPTSMN1; SMN2IDO1AGXT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4090660-A1 | QUINOXALINE DERIVATIVES | Grünenthal GmbH (DE) | 2022-11-23 | — | — | EP | disclosed |