Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AMY1A | P0DUB6 | 6/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 3/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10695056 | 0.85 | AMY1A (0.41) | AMY1ATP53MAPTSMN1; SMN2 | |
| SCHEMBL10580031 | 0.83 | AMY1A (0.46) | AMY1AMAPTSMN1; SMN2 | |
| SCHEMBL10577387 | 0.80 | CDK4 (0.39) | AMY1ANR1I2SMN1; SMN2BRD4 | |
| SCHEMBL10575332 | 0.79 | NPC1 (0.36) | AMY1ANR1I2BRD4 | |
| SCHEMBL10575145 | 0.79 | SMN1; SMN2 (0.47) | TP53MAPTSMN1; SMN2 | |
| SCHEMBL10578728 | 0.78 | NR1I2 (0.34) | AMY1ANR1I2BRD4 | |
| SCHEMBL10578118 | 0.75 | SCD (0.46) | MAPTSMN1; SMN2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL11019903 | 0.73 | AMY1A (0.47) | AMY1ATP53MAPTSMN1; SMN2BRD4 | |
| SCHEMBL10577395 | 0.73 | CDK4 (0.45) | AMY1A | |
| SCHEMBL10576208 | 0.72 | AMY1A (0.34) | AMY1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4882342-A | CARDIOVASCULAR DISORDERS | BOEHRINGER MANNHEIM GMBH (DE) | 1989-11-21 | — | — | US | disclosed |
| EP-0266558-A2 | 5-Alkylbenzimidazoles, process for their preparation and medicaments containing them | Roche Diagnostics GmbH (DE) | 1988-05-11 | — | — | EP | disclosed |