Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AMY1A | P0DUB6 | 11/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
| ▸ | MGAM | O43451 | 1/20 | 0.31 |
| ▸ | SI | P14410 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10693982 | 0.84 | AMY1A (0.38) | AMY1AALDH1A1HPGDKDM4EMAPT | |
| SCHEMBL10575328 | 0.83 | AMY1A (0.41) | AMY1AMAPTSMN1; SMN2 | |
| SCHEMBL10695056 | 0.83 | AMY1A (0.41) | AMY1AMAPTSMN1; SMN2 | |
| SCHEMBL10574074 | 0.77 | AMY1A (0.47) | AMY1ASLC2A1 | |
| SCHEMBL11022045 | 0.76 | AMY1A (0.47) | AMY1A | |
| SCHEMBL10576332 | 0.76 | AMY1A (0.38) | AMY1ASLC2A1NPC1RAB9APKM | |
| SCHEMBL11019293 | 0.76 | AMY1A (0.49) | AMY1A | |
| SCHEMBL10577409 | 0.76 | AMY1A (0.36) | AMY1AALDH1A1HPGDKDM4EMAPT | |
| SCHEMBL10573902 | 0.75 | NPC1 (0.54) | ALDH1A1HPGDKDM4EMAPTGAA | |
| SCHEMBL11020728 | 0.75 | AMY1A (0.48) | AMY1AALDH1A1HPGDKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4882342-A | CARDIOVASCULAR DISORDERS | BOEHRINGER MANNHEIM GMBH (DE) | 1989-11-21 | — | — | US | disclosed |