Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AMY1A | P0DUB6 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10693982 | 0.84 | AMY1A (0.38) | AMY1A | |
| SCHEMBL10578360 | 0.81 | AMY1A (0.34) | AMY1A | |
| SCHEMBL10580104 | 0.80 | PDE5A (0.45) | AMY1A | |
| SCHEMBL10574665 | 0.78 | NPBWR1 (0.47) | — | |
| SCHEMBL10574269 | 0.77 | NPC1 (0.48) | — | |
| SCHEMBL10574093 | 0.77 | AMY1A (0.43) | AMY1A | |
| SCHEMBL10575981 | 0.77 | AMY1A (0.31) | AMY1A | |
| SCHEMBL10579199 | 0.76 | — | — | |
| SCHEMBL10572968 | 0.76 | NPC1 (0.35) | AMY1A | |
| SCHEMBL10577353 | 0.76 | NPC1 (0.37) | AMY1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4882342-A | CARDIOVASCULAR DISORDERS | BOEHRINGER MANNHEIM GMBH (DE) | 1989-11-21 | — | — | US | disclosed |
| EP-0266558-A2 | 5-Alkylbenzimidazoles, process for their preparation and medicaments containing them | Roche Diagnostics GmbH (DE) | 1988-05-11 | — | — | EP | disclosed |