Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AMY1A | P0DUB6 | 2/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 2/20 | 0.33 |
| ▸ | LDLR | P01130 | 1/20 | 0.32 |
| ▸ | VSIR | Q9H7M9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10575328 | 0.85 | AMY1A (0.41) | AMY1AMAPTTP53SMN1; SMN2 | |
| SCHEMBL10580031 | 0.83 | AMY1A (0.46) | AMY1AMAPTSMN1; SMN2 | |
| SCHEMBL10695066 | 0.79 | NPC1 (0.40) | AMY1AMTNR1AMTNR1BMAPT | |
| SCHEMBL10576178 | 0.77 | NPBWR1 (0.46) | MAPTTP53SMN1; SMN2 | |
| SCHEMBL11019903 | 0.77 | AMY1A (0.47) | AMY1AMAPTTP53SMN1; SMN2 | |
| SCHEMBL11018142 | 0.77 | AMY1A (0.43) | AMY1AMAPTTP53SMN1; SMN2 | |
| SCHEMBL10574919 | 0.76 | MTNR1A (0.40) | MTNR1AMTNR1BMAPTSMN1; SMN2ACACB | |
| SCHEMBL11020728 | 0.76 | AMY1A (0.48) | AMY1AMAPTTP53SMN1; SMN2 | |
| SCHEMBL11017268 | 0.75 | CHEK2 (0.47) | AMY1AMAPTTP53SMN1; SMN2 | |
| SCHEMBL10578748 | 0.75 | KDM4E (0.51) | MAPTTP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0266558-A2 | 5-Alkylbenzimidazoles, process for their preparation and medicaments containing them | Roche Diagnostics GmbH (DE) | 1988-05-11 | — | — | EP | disclosed |