Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10695828 | 0.83 | LMNA (0.49) | ADRB2LMNATSHRALDH1A1TDP1 | |
| SCHEMBL10574847 | 0.83 | ESR1 (0.36) | ALDH1A1TDP1POLBMEN1KMT2A | |
| SCHEMBL10577144 | 0.79 | ADRB2 (0.48) | ADRB2LMNATSHRALDH1A1TDP1 | |
| SCHEMBL15157099 | 0.79 | TSHR (0.53) | ADRB2LMNATSHRALDH1A1TDP1 | |
| SCHEMBL9387590 | 0.75 | TSHR (0.59) | ADRB2LMNATSHRALDH1A1TDP1 | |
| SCHEMBL618684 | 0.75 | TSHR (0.59) | ADRB2LMNATSHRALDH1A1TDP1 | |
| SCHEMBL9913609 | 0.75 | TSHR (0.51) | ADRB2LMNATSHRALDH1A1TDP1 | |
| SCHEMBL10575752 | 0.74 | MAPT (0.59) | LMNAALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL4857830 | 0.74 | ALDH1A1 (0.49) | ADRB2LMNATSHRALDH1A1TDP1 | |
| SCHEMBL10385267 | 0.72 | TSHR (0.51) | ADRB2LMNATSHRALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4882342-A | CARDIOVASCULAR DISORDERS | BOEHRINGER MANNHEIM GMBH (DE) | 1989-11-21 | — | — | US | disclosed |
| EP-0266558-A2 | 5-Alkylbenzimidazoles, process for their preparation and medicaments containing them | Roche Diagnostics GmbH (DE) | 1988-05-11 | — | — | EP | disclosed |