Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AMY1A | P0DUB6 | 11/20 | 0.38 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | PDE5A | O76074 | 1/20 | 0.34 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10693991 | 0.92 | AMY1A (0.45) | AMY1APDE5ACHEK2 | |
| SCHEMBL10576332 | 0.92 | AMY1A (0.38) | AMY1ASLC2A1NPC1HSP90AA1PKM | |
| SCHEMBL10696818 | 0.85 | NR1I2 (0.36) | AMY1ASLC2A1NR1I2NPC1HSP90AA1 | |
| SCHEMBL10572968 | 0.84 | NPC1 (0.35) | AMY1ANR1I2NPC1HSP90AA1PKM | |
| SCHEMBL10580044 | 0.83 | AMY1A (0.41) | AMY1ANPC1HSP90AA1PKMRAB9A | |
| SCHEMBL10579198 | 0.79 | ALOX5 (0.53) | AMY1ACHEK2 | |
| SCHEMBL10574074 | 0.79 | AMY1A (0.47) | AMY1ASLC2A1NR1I2HSP90AA1 | |
| SCHEMBL10576214 | 0.77 | AMY1A (0.41) | AMY1ANR1I2NPC1HSP90AA1PKM | |
| SCHEMBL10577353 | 0.77 | NPC1 (0.37) | AMY1ASLC2A1NPC1HSP90AA1PKM | |
| SCHEMBL10761771 | 0.76 | AMY1A (0.41) | AMY1ANPC1HSP90AA1PKMRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4882342-A | CARDIOVASCULAR DISORDERS | BOEHRINGER MANNHEIM GMBH (DE) | 1989-11-21 | — | — | US | disclosed |
| EP-0266558-A2 | 5-Alkylbenzimidazoles, process for their preparation and medicaments containing them | Roche Diagnostics GmbH (DE) | 1988-05-11 | — | — | EP | disclosed |