Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AMY1A | P0DUB6 | 9/20 | 0.41 |
| ▸ | NPBWR1 | P48145 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | PDE5A | O76074 | 1/20 | 0.38 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | PDE2A | O00408 | 1/20 | 0.37 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10576332 | 0.85 | AMY1A (0.38) | AMY1ANPC1HSP90AA1PKMRAB9A | |
| SCHEMBL10748145 | 0.84 | DGAT1 (0.48) | AMY1ANPBWR1PDE5APDE3BPDE3A | |
| SCHEMBL10760630 | 0.80 | CDK4 (0.43) | AMY1ANPBWR1PDE5APDE3BPDE3A | |
| SCHEMBL10765920 | 0.80 | AMY1A (0.39) | AMY1ANPBWR1PDE5APDE3BPDE3A | |
| SCHEMBL10577353 | 0.80 | NPC1 (0.37) | AMY1ANPC1HSP90AA1PKMRAB9A | |
| SCHEMBL10760601 | 0.80 | MAPK10 (0.42) | AMY1ANPC1HSP90AA1PKMRAB9A | |
| SCHEMBL10766038 | 0.79 | NPBWR1 (0.58) | NPBWR1NPC1RAB9ADGAT1KCNH2 | |
| SCHEMBL10575332 | 0.79 | NPC1 (0.36) | AMY1ANPC1HSP90AA1PKMRAB9A | |
| SCHEMBL10695066 | 0.79 | NPC1 (0.40) | AMY1ANPC1HSP90AA1PKMRAB9A | |
| SCHEMBL10759746 | 0.79 | NPC1 (0.44) | AMY1ANPC1HSP90AA1PKMRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0209707-A2 | 2-Aryl imidazoles, pharmaceutical compositions containing them and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1987-01-28 | — | — | EP | disclosed |