Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AMY1A | P0DUB6 | 12/20 | 0.41 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.40 |
| ▸ | PDE5A | O76074 | 1/20 | 0.38 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
| ▸ | PLG | P00747 | 1/20 | 0.37 |
| ▸ | PLAU | P00749 | 1/20 | 0.37 |
| ▸ | PLAT | P00750 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10693991 | 0.92 | AMY1A (0.45) | AMY1ACHEK2PDE5AF2F10 | |
| SCHEMBL10576332 | 0.92 | AMY1A (0.38) | AMY1ACHEK2PDE5APDE3BPDE3A | |
| SCHEMBL10574081 | 0.85 | AMY1A (0.56) | AMY1ANPBWR1 | |
| SCHEMBL10575337 | 0.84 | AMY1A (0.37) | AMY1ACHEK2PDE5APDE3BPDE3A | |
| SCHEMBL10695069 | 0.84 | NPC1 (0.40) | AMY1ACHEK2PDE5APDE3BPDE3A | |
| SCHEMBL10575959 | 0.83 | AMY1A (0.38) | AMY1ACHEK2PDE5ANPC1HSP90AA1 | |
| SCHEMBL10579204 | 0.77 | ALOX5 (0.62) | AMY1ACHEK2NPBWR1TRPV1 | |
| SCHEMBL11022051 | 0.77 | CHEK2 (0.66) | CHEK2 | |
| SCHEMBL10574074 | 0.77 | AMY1A (0.47) | AMY1AHSP90AA1 | |
| SCHEMBL10576214 | 0.77 | AMY1A (0.41) | AMY1ACHEK2NPC1HSP90AA1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4882342-A | CARDIOVASCULAR DISORDERS | BOEHRINGER MANNHEIM GMBH (DE) | 1989-11-21 | — | — | US | disclosed |