Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10577410 | 0.92 | FGFR1 (0.36) | HDAC6 | |
| SCHEMBL10577938 | 0.83 | ALDH1A1 (0.47) | HDAC6 | |
| SCHEMBL10578437 | 0.81 | HDAC6 (0.35) | HDAC6 | |
| SCHEMBL10571887 | 0.81 | KIT (0.39) | HDAC6 | |
| SCHEMBL10578441 | 0.80 | HDAC6 (0.46) | HDAC6 | |
| SCHEMBL10580688 | 0.80 | HDAC6 (0.52) | HDAC6 | |
| SCHEMBL10575294 | 0.80 | METAP2 (0.31) | HDAC6 | |
| SCHEMBL10578822 | 0.80 | HDAC6 (0.30) | HDAC6 | |
| SCHEMBL10573014 | 0.80 | METAP2 (0.31) | HDAC6 | |
| SCHEMBL10574665 | 0.79 | NPBWR1 (0.47) | HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4882342-A | CARDIOVASCULAR DISORDERS | BOEHRINGER MANNHEIM GMBH (DE) | 1989-11-21 | — | — | US | disclosed |
| EP-0266558-A2 | 5-Alkylbenzimidazoles, process for their preparation and medicaments containing them | Roche Diagnostics GmbH (DE) | 1988-05-11 | — | — | EP | disclosed |