SCHEMBL6129338

SCHEMBL6129338

O=C(CCl)c1ccccc1O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.54
HPGD P15428 5/20 0.54
ALDH1A1 P00352 4/20 0.54
SMN1; SMN2 Q16637 3/20 0.54
CA12 O43570 1/20 0.54
CA1 P00915 1/20 0.54
CA2 P00918 1/20 0.54
HMGB1 P09429 1/20 0.54
CA4 P22748 1/20 0.54
CA6 P23280 1/20 0.54
CA7 P43166 1/20 0.54
CA9 Q16790 1/20 0.54
NAPRT Q6XQN6 1/20 0.54
CA14 Q9ULX7 1/20 0.54
MAPT P10636 5/20 0.52
TSHR P16473 3/20 0.52
HIF1A Q16665 2/20 0.52
TRPA1 O75762 1/20 0.52
MAPK1 P28482 1/20 0.52
GSK3B P49841 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11737575 0.85 ALDH1A1 (0.61) KDM4EALDH1A1SMN1; SMN2MAPTHIF1A
SCHEMBL2788116 0.83 ALOX5 (0.55) KDM4EHPGDALDH1A1SMN1; SMN2CA12
SCHEMBL31211720 0.81 CYP19A1 (0.66) KDM4EHPGDALDH1A1SMN1; SMN2CA12
SCHEMBL105808 0.81 KDM4E (0.58) KDM4EHPGDALDH1A1SMN1; SMN2CA12
SCHEMBL598345 0.81 MEN1 (0.69) KDM4EHPGDALDH1A1SMN1; SMN2CA12
SCHEMBL21055978 0.81 TSHR (0.45) KDM4EHPGDALDH1A1SMN1; SMN2CA12
SCHEMBL5520169 0.79 CYP19A1 (0.54) KDM4EHPGDALDH1A1SMN1; SMN2CA12
SCHEMBL7826271 0.79 KDM4E (0.56) KDM4EHPGDALDH1A1SMN1; SMN2CA12
SCHEMBL1896351 0.77 ALDH1A1 (0.64) KDM4EHPGDALDH1A1SMN1; SMN2CA12
SCHEMBL976846 0.77 CES2 (0.60) KDM4EHPGDALDH1A1SMN1; SMN2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 108 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114751870-B 2- (isoxazole-5-yl) phenyl-3, 4-dihydroxybenzoate and derivative thereof, and synthetic method and application thereof 贵州医科大学 2023-10-20 CN claimed
CN-114751870-A 2- (isoxazole-5-yl) phenyl-3, 4-dihydroxy benzoate and derivative thereof, and synthesis method and application thereof 贵州医科大学 2022-07-15 CN claimed
JP-56104835-A None JP disclosed
CN-119841849-A Pyridone compound, synthesis method and application thereof 浙江大学 2025-04-18 CN disclosed
CN-119343126-A Skin barrier protection delivery system and method thereof 宝宝实验室公司 2025-01-21 CN disclosed
CN-118638089-B Preparation method for synthesizing flavonoid compound based on carbon dioxide 湖南工程学院 2024-11-12 CN disclosed
CN-118638089-A Preparation method for synthesizing flavonoid compound based on carbon dioxide 湖南工程学院 2024-09-13 CN disclosed
CN-118401503-A Process for the preparation of benzofurans 坎布雷普佛马可米兰有限公司 2024-07-26 CN disclosed
CN-114805224-B Ligustrazine chalcone derivative and preparation method and application thereof 山东大学 2024-03-22 CN disclosed
CN-114751870-B 2- (isoxazole-5-yl) phenyl-3, 4-dihydroxybenzoate and derivative thereof, and synthetic method and application thereof 贵州医科大学 2023-10-20 CN disclosed
WO-2023110528-A1 PROCESS FOR THE PREPARATION OF BENZOFURANS CAMBREX PROFARMACO MILANO S.R.L. (IT) 2023-06-22 WO disclosed
EP-0257700-A2 Improved bleaching or detergent bleach composition UNILEVER N.V. (NL) 1988-03-02 EP disclosed
EP-0217454-A2 Non-aqueous liquid detergent composition and perborate anhydrous UNILEVER N.V. (NL) 1987-04-08 EP disclosed
US-4551554-A PHENOL REACTED WITH HALOACETONITRILE AND BORON COMPOUND SHIONOGI & CO., LTD. (JP) 1985-11-05 US disclosed
EP-0043861-B1 NOVEL PROCESS FOR SYNTHESIZING 2-HALOACETYLPHENOLS SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) 1984-04-25 EP disclosed
US-4374747-A Bleach products LEVER BROTHERS COMPANY (US) 1983-02-22 US disclosed
EP-0018678-B1 BLEACH PRODUCTS UNILEVER N.V. (NL) 1982-04-07 EP disclosed
EP-0043861-A1 NOVEL PROCESS FOR SYNTHESIZING 2-HALOACETYLPHENOLS SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) 1982-01-20 EP disclosed
JP-S56104835-A NOVEL SYNTHESIS OF 2-HALOACETYLPHENOLS SHIONOGI & CO LTD 1981-08-20 JP disclosed
EP-0018678-A1 Bleach products UNILEVER N.V. (NL) 1980-11-12 EP disclosed