Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 4/20 | 0.37 |
| ▸ | RECQL | P46063 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10583125 | 1.00 | MAPT (0.41) | MAPTSMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL10581813 | 0.81 | MAPT (0.43) | MAPTSMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL9113733 | 0.79 | MAPT (0.44) | MAPTLMNAMEN1KMT2AMAPK1 | |
| SCHEMBL10581369 | 0.78 | HTT (0.51) | MAPTLMNAMEN1KMT2AMAPK1 | |
| SCHEMBL988312 | 0.72 | LMNA (0.50) | MAPTSMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL988797 | 0.72 | LMNA (0.44) | MAPTSMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL988796 | 0.72 | LMNA (0.44) | MAPTSMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL10621299 | 0.72 | MAPT (0.34) | MAPTSMN1; SMN2LMNAALOX15ALOX12 | |
| SCHEMBL9820264 | 0.71 | TDP1 (0.42) | MAPTSMN1; SMN2MEN1KMT2AALOX15 | |
| SCHEMBL27612062 | 0.69 | RAB9A (0.48) | MAPTSMN1; SMN2LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4888445-A | New 2,4-dinitro- or 2-amino-4-nitro- or 2-nitro-4-amino-6-hydroxyalkylanilines, the process for preparation thereof and their use in dyeing keratinous fibres, and especially human hair | L'OREAL (FR) | 1989-12-19 | — | — | US | disclosed |