SCHEMBL10583289

SCHEMBL10583289

OCC(Br)c1c(F)c(F)cc(F)c1F

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.32
CA2 P00918 2/20 0.32
CA4 P22748 2/20 0.32
CES2 O00748 1/20 0.30
CES1 P23141 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9505375 0.80
SCHEMBL16585941 0.73 CES2 (0.39) CES2CES1
SCHEMBL10583405 0.73 CA1 (0.32) CA1CA2CA4CES2CES1
SCHEMBL3199864 0.67 ADRB2 (0.31) CA1CA2CA4CES2CES1
SCHEMBL7152606 0.64 ADRA2C (0.50)
SCHEMBL1996784 0.64 MEN1 (0.37) CA1CA2CA4CES2CES1
SCHEMBL22561829 0.64 CA1 (0.31) CA1CA2CA4
SCHEMBL9003976 0.62 CA1 (0.33) CA1CA2CA4CES2CES1
SCHEMBL30685046 0.62 CA1 (0.33) CA1CA2CA4CES2CES1
SCHEMBL358960 0.62 CA1 (0.39) CA1CA2CA4CES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0302612-A1 Insecticidal compounds characterised by enhanced knockdown effect IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1989-02-08 EP disclosed
EP-0302626-A2 Insecticidal compounds IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1989-02-08 EP disclosed