Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | MIF | P14174 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MMP12 | P39900 | 2/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10532639 | 1.00 | RXRA (0.40) | RXRAGAAMIFMAPTMMP12 | |
| SCHEMBL9421054 | 1.00 | RXRA (0.40) | RXRAGAAMIFMAPTMMP12 | |
| SCHEMBL9421063 | 1.00 | RXRA (0.40) | RXRAGAAMIFMAPTMMP12 | |
| SCHEMBL9421097 | 0.84 | MMP12 (0.42) | RXRAMIFMAPTMMP12MMP13 | |
| SCHEMBL9421091 | 0.84 | MMP12 (0.42) | RXRAMIFMAPTMMP12MMP13 | |
| SCHEMBL9421153 | 0.84 | MMP12 (0.42) | RXRAMIFMAPTMMP12MMP13 | |
| SCHEMBL9421103 | 0.84 | MMP12 (0.42) | RXRAMIFMAPTMMP12MMP13 | |
| SCHEMBL9421148 | 0.84 | MMP12 (0.42) | RXRAMIFMAPTMMP12MMP13 | |
| SCHEMBL9421081 | 0.73 | LMNA (0.42) | GAAMAPTALDH1A1HTTLMNA | |
| SCHEMBL9421084 | 0.73 | LMNA (0.42) | GAAMAPTALDH1A1HTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0312269-A2 | 3,5-Dihydroxy-6,8-nonadienoic acids and derivatives as hypocholesterolemic agents | PFIZER INC. (US) | 1989-04-19 | — | — | EP | disclosed |