Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.61 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.61 |
| ▸ | DRD3 | P35462 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 7/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.61 |
| ▸ | MEN1 | O00255 | 4/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.56 |
| ▸ | SLC15A2 | Q16348 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | ESR1 | P03372 | 1/20 | 0.56 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.56 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.56 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.56 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10586264 | 0.90 | PTGS2 (0.77) | DRD2PTGS2DRD3MAPTALDH1A1 | |
| SCHEMBL10586256 | 0.90 | PTGS2 (0.77) | DRD2PTGS2DRD3MAPTALDH1A1 | |
| SCHEMBL10529189 | 0.87 | MAPT (0.75) | DRD2PTGS2DRD3MAPTALDH1A1 | |
| SCHEMBL10529194 | 0.87 | MAPT (0.75) | DRD2PTGS2DRD3MAPTALDH1A1 | |
| SCHEMBL11585032 | 0.85 | ALDH1A1 (0.73) | DRD2PTGS2DRD3MAPTALDH1A1 | |
| SCHEMBL11587336 | 0.85 | ALDH1A1 (0.73) | DRD2PTGS2DRD3MAPTALDH1A1 | |
| SCHEMBL11585026 | 0.85 | ALDH1A1 (0.73) | DRD2PTGS2DRD3MAPTALDH1A1 | |
| SCHEMBL11587339 | 0.85 | ALDH1A1 (0.73) | DRD2PTGS2DRD3MAPTALDH1A1 | |
| SCHEMBL11586741 | 0.84 | DRD2 (0.61) | DRD2PTGS2DRD3MAPTALDH1A1 | |
| SCHEMBL11586739 | 0.84 | DRD2 (0.61) | DRD2PTGS2DRD3MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0321364-A2 | Orally administrable cephalosporin derivatives, and the production and uses thereof | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1989-06-21 | — | — | EP | claimed |