SCHEMBL1058699

SCHEMBL1058699

C=Cc1cc(CC)cc2ccccc12

nearest known ligand 0.46

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.46
CYP2A6 P11509 2/20 0.46
HTR6 P50406 1/20 0.43
TP53 P04637 1/20 0.35
GAA P10253 1/20 0.35
KIF11 P52732 1/20 0.35
ALDH1A1 P00352 2/20 0.33
HTR2A P28223 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
HIF1A Q16665 1/20 0.33
CYP1B1 Q16678 1/20 0.33
HSD17B10 Q99714 1/20 0.33
MAPT P10636 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
HPGD P15428 1/20 0.33
SIGMAR1 Q99720 1/20 0.33
TSHR P16473 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5034581 0.86 GAA (0.37) CYP1A2CYP2A6HTR6GAAALDH1A1
SCHEMBL10700831 0.86 HTR6 (0.35) CYP1A2CYP2A6HTR6MAPTSMN1; SMN2
SCHEMBL9680135 0.85 HTR6 (0.34) CYP1A2CYP2A6HTR6GAAALDH1A1
SCHEMBL7714016 0.83 MAPT (0.36) CYP1A2CYP2A6HTR6ALDH1A1L3MBTL1
SCHEMBL3267425 0.82 CYP1A2 (0.46) CYP1A2CYP2A6HTR6GAAALDH1A1
SCHEMBL4590405 0.82 TSHR (0.35) CYP1A2ALDH1A1HTR2AL3MBTL1HIF1A
SCHEMBL4521095 0.81 CYP1A2 (0.48) CYP1A2CYP2A6HTR6GAAKIF11
SCHEMBL10384829 0.79 PTGS1 (0.39) CYP1A2CYP2A6GAAMAPTSMN1; SMN2
SCHEMBL21045089 0.76 CYP1A2 (0.55) CYP1A2CYP2A6TP53GAAALDH1A1
SCHEMBL7188805 0.75 HTR2A (0.41) CYP1A2CYP2A6ALDH1A1HTR2AL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 403 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3822308-B1 RECYCLED RUBBER IND TECH RES INST (TW) 2025-03-05 EP claimed
US-12195561-B2 Bissilylamino-functionalized conjugated dienes, their preparation and their use in the production of rubbers SYNTHOS S.A. (PL) 2025-01-14 US claimed
US-11993620-B2 Aminosilyl-functionalized conjugated dienes, their preparation and their use in the production of rubbers SYNTHOS S.A. (PL) 2024-05-28 US claimed
EP-3915808-B1 FUNCTIONALIZED INITIATOR, METHOD OF MAKING AN INITIATOR AND FUNCTIONALIZED ELASTOMER GOODYEAR TIRE & RUBBER (US) 2024-01-31 EP claimed
CN-113329890-B Bis-silylamino functionalized conjugated dienes, preparation thereof and use thereof in rubber production 西索斯公司 2023-10-20 CN claimed
CN-112812358-B Reclaimed rubber 财团法人工业技术研究院 2023-05-09 CN claimed
EP-3911525-B1 BISSILYLAMINO-FUNCTIONALIZED CONJUGATED DIENES, THEIR PREPARATION AND THEIR USE IN THE PRODUCTION OF RUBBERS Synthos Sa (PL) 2023-03-08 EP claimed
CN-112955332-B Amino silyl functionalized conjugated dienes, their preparation and use in the manufacture of rubber 西索斯公司 2023-02-21 CN claimed
EP-3774953-B1 MIXTURES OF AMINOSILYL-FUNCTIONALIZED STYRENES, THEIR PREPARATION AND THEIR USE IN THE PRODUCTION OF ELASTOMERIC COPOLYMERS Synthos Sa (PL) 2022-05-04 EP claimed
US-11312843-B2 Bissilylaminosilyl-functionalized conjugated dienes and their use in the production of rubbers SYNTHOS DWORY 7 SPOLKA Z OGRANICZONA ODPOWIEDZIALNOSCIA SPOLKA JAWNA 2022-04-26 US claimed
WO-2019030064-A1 BISSILYLAMINOSILYL-FUNCTIONALIZED CONJUGATED DIENES AND THEIR USE IN THE PRODUCTION OF RUBBERS SYNTHOS DWORY 7 SPOLKA Z OGRANICZONA ODPOWIEDZIALNOSCIA SPOLKA JAWNA (PL) 2019-02-14 WO claimed
WO-2018178199-A1 POLAR ADDITIVE FOR THE SYNTHESIS OF COPOLYMERS OF VINYLAROMATIC MONOMER AND CONJUGATED DIENE MONOMER HAVING HIGH VINYLAROMATIC AND LOW VINYL CONTENTS SYNTHOS S.A. (PL) 2018-10-04 WO claimed
EP-3341424-A1 ELASTOMERIC COPOLYMERS BASED ON [BIS(TRIHYDROCARBYLSILYL)AMINOSILYL]-FUNCTIONALIZED STYRENE AND THEIR USE IN THE PREPARATION OF RUBBERS Synthos S.A. (PL) 2018-07-04 EP claimed
WO-2018065494-A1 ELASTOMERIC COPOLYMERS BASED ON [BIS(TRIHYDROCARBYLSILYL)AMINOSILYL]-FUNCTIONALIZED STYRENE AND THEIR USE IN THE PREPARATION OF RUBBERS SYNTHOS S.A. (PL) 2018-04-12 WO claimed
US-20180072101-A1 ELASTOMERIC COPOLYMERS BASED ON [BIS(TRIHYDROCARBYLSILYL)AMINOSILYL]-FUNCTIONALIZED STYRENE AND THEIR USE IN THE PREPARATION OF RUBBERS SYNTHOS S.A. (PL) 2018-03-15 US claimed
EP-3280766-A1 ELASTOMERIC COPOLYMERS BASED ON [BIS(TRIHYDROCARBYLSILYL)AMINOSILYL]-FUNCTIONALIZED STYRENE AND THEIR USE IN THE PREPARATION OF RUBBERS Synthos S.A. (PL) 2018-02-14 EP claimed
WO-2016162528-A1 ELASTOMERIC COPOLYMERS BASED ON [BIS(TRIHYDROCARBYLSILYL)AMINOSILYL]-FUNCTIONALIZED STYRENE AND THEIR USE IN THE PREPARATION OF RUBBERS SYNTHOS S.A. (PL) 2016-10-13 WO claimed
US-7485684-B2 Functionalization of living rubbery polymers with nitrones THE GOODYEAR TIRE & RUBBER COMPANY (US) 2009-02-03 US claimed
US-20070004869-A1 Functionalization of living rubbery polymers with nitrones THE GOODYEAR TIRE & RUBBER COMPANY (US) 2007-01-04 US claimed
US-4845154-A TIRE TREAD SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) 1989-07-04 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180072101-A1 ELASTOMERIC COPOLYMERS BASED ON [BIS(TRIHYDROCARBYLSILYL)AMINOSILYL]-FUNCTIONALIZED STYRENE AND THEIR USE IN THE PREPARATION OF RUBBERS VCL, TIPRL, TTL CYP1A2 2276/4885CYP2A6 2732/4885HTR6 1597/4885
US-12195561-B2 Bissilylamino-functionalized conjugated dienes, their preparation and their use in the production of rubbers CARM1, ILK, RIF1 CYP1A2 188/4885CYP2A6 1313/4885HTR6 3827/4885
US-11993620-B2 Aminosilyl-functionalized conjugated dienes, their preparation and their use in the production of rubbers LTA, RALA, BOLA2; BOLA2B CYP1A2 609/4885CYP2A6 1402/4885HTR6 3929/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.