Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MPI | P34949 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 2/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1058699 | 0.83 | CYP1A2 (0.46) | MAPTALDH1A1HPGDCYP1A2SMN1; SMN2 | |
| SCHEMBL6667221 | 0.80 | ALDH1A1 (0.41) | MAPTALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL9680135 | 0.75 | HTR6 (0.34) | ALDH1A1HPGDCYP1A2HTR6CYP2A6 | |
| SCHEMBL4590405 | 0.74 | TSHR (0.35) | MAPTALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL4521095 | 0.72 | CYP1A2 (0.48) | MAPTALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL5034581 | 0.71 | GAA (0.37) | MAPTALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL10700831 | 0.71 | HTR6 (0.35) | MAPTCYP1A2SMN1; SMN2HTR6CYP2A6 | |
| SCHEMBL10384829 | 0.71 | PTGS1 (0.39) | MAPTCYP1A2SMN1; SMN2CYP2A6SIGMAR1 | |
| SCHEMBL1237477 | 0.70 | CES1 (0.41) | MAPTALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL23722665 | 0.70 | MAPT (0.43) | MAPTALDH1A1CYP1A2SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-H2030-H1 | Process for the preparation of random copolymers of conjugated dienes and vinyl aromatic compounds | SHELL OIL COMPANY | 2002-06-04 | — | — | US | disclosed |
| EP-0413403-B1 | Process for the preparation of copolymers of conjugated dienes and vinyl aromatic compounds | SHELL INT RESEARCH (NL) | 1999-07-07 | — | — | EP | disclosed |
| US-5336737-A | Initiator based on lithium, in the presence of an inert solvent | SHELL OIL COMPANY (US) | 1994-08-09 | — | — | US | disclosed |
| EP-0413403-A1 | Process for the preparation of copolymers of conjugated dienes and vinyl aromatic compounds | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1991-02-20 | — | — | EP | disclosed |