Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHCY | P23526 | 3/20 | 0.59 |
| ▸ | MARS1 | P56192 | 1/20 | 0.59 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.58 |
| ▸ | P2RY1 | P47900 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | SRC | P12931 | 2/20 | 0.58 |
| ▸ | P2RY2 | P41231 | 2/20 | 0.58 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.58 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.58 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.58 |
| ▸ | LDHA | P00338 | 1/20 | 0.58 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.58 |
| ▸ | FBP1 | P09467 | 1/20 | 0.58 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.58 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.58 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.58 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.58 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.58 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6744875 | 1.00 | AHCY (0.59) | AHCYMARS1ADORA1P2RY1SMN1; SMN2 | |
| SCHEMBL19889158 | 0.92 | ALDH1A1 (0.65) | AHCYMARS1ADORA1P2RY1SMN1; SMN2 | |
| SCHEMBL8205660 | 0.92 | ALDH1A1 (0.65) | AHCYMARS1ADORA1P2RY1SMN1; SMN2 | |
| SCHEMBL31685764 | 0.92 | ALDH1A1 (0.65) | AHCYMARS1ADORA1P2RY1SMN1; SMN2 | |
| SCHEMBL10033986 | 0.92 | ALDH1A1 (0.65) | AHCYMARS1ADORA1P2RY1SMN1; SMN2 | |
| SCHEMBL23982402 | 0.92 | ALDH1A1 (0.65) | AHCYMARS1ADORA1P2RY1SMN1; SMN2 | |
| SCHEMBL11423681 | 0.92 | ALDH1A1 (0.65) | AHCYMARS1ADORA1P2RY1SMN1; SMN2 | |
| SCHEMBL13597931 | 0.92 | ALDH1A1 (0.65) | AHCYMARS1ADORA1P2RY1SMN1; SMN2 | |
| SCHEMBL4425824 | 0.92 | ALDH1A1 (0.65) | AHCYMARS1ADORA1P2RY1SMN1; SMN2 | |
| SCHEMBL5551928 | 0.90 | ADORA3 (0.69) | AHCYADORA1P2RY1SMN1; SMN2SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4048432-A | 9-(3,5-Di-O-acyl-β-D-arabinofuranosyl)adenine compounds and method for their production | PARKE, DAVIS & COMPANY (US) | 1977-09-13 | — | — | US | claimed |
| EP-0317728-A2 | Use of 9-(beta-D-arabinofuranosyl) adenine derivatives for the preparation of pharmaceutical compositions for the treatment of aids | WARNER-LAMBERT COMPANY (US) | 1989-05-31 | — | — | EP | disclosed |
| US-4048432-A | 9-(3,5-Di-O-acyl-β-D-arabinofuranosyl)adenine compounds and method for their production | PARKE, DAVIS & COMPANY (US) | 1977-09-13 | — | — | US | disclosed |