Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.38 |
| ▸ | MLYCD | O95822 | 3/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | RARB | P10826 | 1/20 | 0.34 |
| ▸ | RARG | P13631 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10031827 | 0.87 | PGR (0.47) | PGRARHDAC1SRD5A2MLYCD | |
| SCHEMBL5927848 | 0.81 | HDAC1 (0.59) | HDAC1HDAC6SRD5A2CA2RAB9A | |
| SCHEMBL3050432 | 0.81 | CES2 (0.54) | PGRARHDAC1HDAC6CA2 | |
| SCHEMBL2574286 | 0.80 | CES2 (0.52) | PGRARHDAC6MLYCDELANE | |
| SCHEMBL15745797 | 0.80 | PGR (0.51) | PGRARCA2ELANERAB9A | |
| SCHEMBL10483771 | 0.80 | ELANE (0.54) | PGRARSRD5A2ELANERAB9A | |
| SCHEMBL5058744 | 0.80 | PGR (0.43) | PGRARHDAC1SRD5A2MLYCD | |
| SCHEMBL9178565 | 0.79 | HDAC1 (0.47) | PGRARHDAC1HDAC6MLYCD | |
| SCHEMBL547696 | 0.79 | HDAC1 (0.42) | PGRARHDAC1HDAC6SRD5A2 | |
| SCHEMBL688186 | 0.79 | TP53 (0.47) | HDAC6SRD5A2CA2ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0319316-A2 | Griseolic acid monoesters, their preparation and use | SANKYO COMPANY LIMITED (JP) | 1989-06-07 | — | — | EP | disclosed |