SCHEMBL10031827

SCHEMBL10031827

CC(C)(C)C(=O)c1ccc(C(=O)C(C)(C)C)cc1

nearest known ligand 0.47

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PGR P06401 1/20 0.47
AR P10275 1/20 0.47
ELANE P08246 3/20 0.43
CA2 P00918 1/20 0.43
HDAC1 Q13547 1/20 0.41
CES1 P23141 3/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
TP53 P04637 1/20 0.40
TSHR P16473 1/20 0.40
SRD5A2 P31213 1/20 0.39
ALDH1A1 P00352 2/20 0.39
LMNA P02545 1/20 0.39
CES2 O00748 1/20 0.39
MLYCD O95822 4/20 0.39
SMN1; SMN2 Q16637 1/20 0.38
MAPK1 P28482 1/20 0.38
SRC P12931 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15745797 0.92 PGR (0.51) PGRARELANECA2L3MBTL1
SCHEMBL10483771 0.92 ELANE (0.54) PGRARELANESRD5A2ALDH1A1
SCHEMBL5058744 0.92 PGR (0.43) PGRARELANECA2HDAC1
SCHEMBL11823338 0.89 MAPT (0.50) PGRARL3MBTL1ALDH1A1LMNA
SCHEMBL759623 0.89 ESR1 (0.52) ARELANECA2TSHRSRD5A2
SCHEMBL11437940 0.89 PGR (0.42) PGRARELANECA2HDAC1
SCHEMBL1665113 0.89 TSHR (0.60) CA2CES1TP53TSHRSRD5A2
SCHEMBL1665111 0.89 PGR (0.42) PGRARELANECA2HDAC1
SCHEMBL1701967 0.89 CA2 (0.57) CA2HDAC1CES1SRD5A2ALDH1A1
SCHEMBL24354428 0.87 TPMT (0.52) PGRARELANECA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230399459-A1 LIQUID CRYSTAL POLYMER COMPOSITIONS, ARTICLES AND METHODS OF MAKING SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2023-12-14 US disclosed
US-20230310551-A1 INSULIN RECEPTOR PARTIAL AGONISTS MERCK SHARP & DOHME LLC (US) 2023-10-05 US disclosed
US-20230312915-A1 PRODUCTION PROCESS OF POLYESTER MICROPOWDERS SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2023-10-05 US disclosed
US-20230310551-A1 INSULIN RECEPTOR PARTIAL AGONISTS MERCK SHARP & DOHME LLC (US) 2023-10-05 US disclosed
EP-4249203-A1 RESIN-MADE PIPE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2023-09-27 EP disclosed
US-11767620-B2 Braided cord with changing cross-sectional area KURARAY CO., LTD. (JP) 2023-09-26 US disclosed
US-11674246-B2 Braided jackets with low thickness KURARAY CO., LTD. (JP) 2023-06-13 US disclosed
US-20230135721-A1 MEMBRANE PROCESS FOR NATURAL GAS LIQUIDS RECOVERY AND HYDROCARBON DEW POINT CONTROL AIR LIQUIDE ADVANCED TECHNOLOGIES U.S. LLC (US) 2023-05-04 US disclosed
WO-2023012328-A1 COMPOSITE FILMS FOR MOBILE ELECTRONIC DEVICE COMPONENTS SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2023-02-09 WO disclosed
WO-2023006415-A1 POLYMER COMPOSITION AND ARTICLES MADE THEREFROM SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2023-02-02 WO disclosed
US-20140256694-A1 STEROID ANTIBIOTIC CONJUGATES ALLERGAN, INC. (US) 2014-09-11 US disclosed
US-8802683-B2 Compounds for use in treatment of mucositis CELLCEUTIX CORPORATION (US) 2014-08-12 US disclosed
US-20140148548-A1 Fluorine-Containing Polymerizable Monomer And Polymer Compound Using Same CENTRAL GLASS COMPANY, LIMITED (JP) 2014-05-29 US disclosed
US-20120295922-A1 Compounds For Use In Treatment Of Mucositis POLYMEDIX, INC. (US) 2012-11-22 US disclosed
US-20120258141-A9 Methods Of Immune Modulation UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY (US) 2012-10-11 US disclosed
US-8206893-B2 Photoimageable branched polymer BREWER SCIENCE INC. (US) 2012-06-26 US disclosed
US-20120039945-A1 Methods Of Immune Modulation UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY (US) 2012-02-16 US disclosed
EP-2384803-A1 FILTRATION MATERIAL FOR FILTERS, AND FILTER CARTRIDGE Kuraray Co., Ltd. (JP) 2011-11-09 EP disclosed
US-20110178104-A1 Anti-Heparin Compounds POLYMEDIX INC. (US) 2011-07-21 US disclosed
US-20090111057-A1 PHOTOIMAGEABLE BRANCHED POLYMER BREWER SCIENCE INC. 2009-04-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140256694-A1 STEROID ANTIBIOTIC CONJUGATES CYP17A1, CYP21A2, HSD17B1 PGR 1768/4885AR 514/4885ELANE 891/4885
US-20120295922-A1 Compounds For Use In Treatment Of Mucositis MUC1, FUT6, MMP8 PGR 2887/4885AR 4590/4885ELANE 21/4885
US-20120258141-A9 Methods Of Immune Modulation IFNG, CD14, TLR3 PGR 2031/4885AR 3646/4885ELANE 416/4885
US-20120039945-A1 Methods Of Immune Modulation IFNG, CD14, TLR3 PGR 2031/4885AR 3646/4885ELANE 416/4885
US-20110178104-A1 Anti-Heparin Compounds SERPINC1, CFH, SERPINH1 PGR 2996/4885AR 4472/4885ELANE 31/4885
US-20140148548-A1 Fluorine-Containing Polymerizable Monomer And Polymer Compound Using Same AFF4, AFF2, AFF1 PGR 3175/4885AR 3376/4885ELANE 2745/4885
US-20230310551-A1 INSULIN RECEPTOR PARTIAL AGONISTS INSR, GPR119, IRS1 PGR 293/4885AR 159/4885ELANE 2560/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.