Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | MMP1 | P03956 | 6/20 | 0.58 |
| ▸ | MMP2 | P08253 | 6/20 | 0.58 |
| ▸ | MMP9 | P14780 | 6/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | NPC1 | O15118 | 3/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.57 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.57 |
| ▸ | RELA | Q04206 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.55 |
| ▸ | ACHE | P22303 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10587887 | 1.00 | SMN1; SMN2 (0.62) | SMN1; SMN2ALDH1A1MMP1MMP2MMP9 | |
| SCHEMBL10588017 | 0.89 | MAPT (0.58) | SMN1; SMN2ALDH1A1MMP1MMP2MMP9 | |
| SCHEMBL10588022 | 0.89 | MAPT (0.58) | SMN1; SMN2ALDH1A1MMP1MMP2MMP9 | |
| SCHEMBL10478111 | 0.86 | MAPT (0.58) | SMN1; SMN2ALDH1A1MMP1MMP2MMP9 | |
| SCHEMBL9312217 | 0.86 | MAPT (0.58) | SMN1; SMN2ALDH1A1MMP1MMP2MMP9 | |
| SCHEMBL9312484 | 0.85 | ALDH1A1 (0.59) | SMN1; SMN2ALDH1A1MMP1MMP2MMP9 | |
| SCHEMBL9312489 | 0.85 | ALDH1A1 (0.59) | SMN1; SMN2ALDH1A1MMP1MMP2MMP9 | |
| SCHEMBL9312296 | 0.81 | MMP1 (0.57) | ALDH1A1MMP1MMP2MMP9MAPT | |
| SCHEMBL9312300 | 0.81 | MMP1 (0.57) | ALDH1A1MMP1MMP2MMP9MAPT | |
| SCHEMBL10585350 | 0.77 | MAOB (0.54) | ALDH1A1MAPTTRPV1ACHEKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0327986-A2 | Medicaments containing lactams, substituted lactams and process for their preparation | Roche Diagnostics GmbH (DE) | 1989-08-16 | — | — | EP | disclosed |