Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.32 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
| ▸ | DHODH | Q02127 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | TKT | P29401 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10588773 | 0.85 | TAAR1 (0.36) | LMNAHTTL3MBTL1CYP1A2PTK2 | |
| SCHEMBL9769158 | 0.84 | CCNE1 (0.39) | LMNAHTTL3MBTL1POLBCCNE1 | |
| SCHEMBL9605493 | 0.77 | L3MBTL1 (0.39) | LMNAHTTL3MBTL1CYP1A2PTK2 | |
| SCHEMBL6324850 | 0.72 | DHODH (0.54) | LMNAHTTL3MBTL1CYP1A2POLB | |
| SCHEMBL2275255 | 0.72 | MEN1 (0.43) | LMNAHTTL3MBTL1CYP1A2PTK2 | |
| SCHEMBL13304496 | 0.70 | ADORA3 (0.46) | LMNAHTTL3MBTL1CYP1A2PTK2 | |
| SCHEMBL14069596 | 0.70 | LMNA (0.45) | LMNAHTTL3MBTL1CYP1A2PTK2 | |
| SCHEMBL10588266 | 0.69 | L3MBTL1 (0.44) | LMNAHTTL3MBTL1CYP1A2PTK2 | |
| SCHEMBL18610938 | 0.69 | L3MBTL1 (0.44) | LMNAHTTL3MBTL1CYP1A2PTK2 | |
| SCHEMBL12618024 | 0.69 | CYP1A2 (0.52) | LMNAHTTCYP1A2POLBADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0325131-A2 | Pyrimidine derivatives as performance stimulating agents | BAYER AG (DE) | 1989-07-26 | — | — | EP | disclosed |