Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3878819 | 0.98 | TSHR (0.42) | TSHRALDH1A1LMNAAPEX1TDP1 | |
| Hydrochloric Acid SCHEMBL3963896 | 0.95 | ALDH1A1 (0.44) | TSHRALDH1A1LMNAAPEX1TDP1 | |
| Hydrochloric Acid SCHEMBL10871497 | 0.80 | ALDH1A1 (0.48) | TSHRALDH1A1LMNAAPEX1TDP1 | |
| SCHEMBL10481784 | 0.77 | BBOX1 (0.36) | — | |
| Hydrochloric Acid SCHEMBL8166002 | 0.73 | ACHE (0.41) | TSHRALDH1A1LMNAAPEX1ACHE | |
| Glycinebetaine SCHEMBL7771573 | 0.70 | TSHR (0.44) | TSHRALDH1A1LMNAAPEX1TDP1 | |
| Betaine SCHEMBL5965072 | 0.70 | TSHR (0.64) | TSHRALDH1A1LMNAAPEX1TDP1 | |
| SCHEMBL10435380 | 0.69 | — | — | |
| SCHEMBL5137154 | 0.69 | — | — | |
| SCHEMBL16099432 | 0.67 | CYP2D6 (0.36) | TSHRALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0334126-A2 | Polymeric particles, preparation by colloidally stabilized suspension process, encapsulated toner particles containing them. | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1989-09-27 | — | — | EP | disclosed |