Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | TKT | P29401 | 5/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29895545 | 1.00 | LMNA (0.63) | LMNAKDM4EALDH1A1CYP1A2TSHR | |
| Hydrochloric Acid SCHEMBL479404 | 0.98 | LMNA (0.61) | LMNAKDM4EALDH1A1CYP1A2TSHR | |
| Hydrogen Sulfide SCHEMBL28870746 | 0.98 | LMNA (0.61) | LMNAKDM4EALDH1A1CYP1A2TSHR | |
| Bicarbonate SCHEMBL9320107 | 0.91 | LMNA (0.54) | LMNAKDM4EALDH1A1CYP1A2TSHR | |
| SCHEMBL27959821 | 0.83 | LMNA (0.59) | LMNAKDM4EALDH1A1CYP1A2TSHR | |
| SCHEMBL23748348 | 0.83 | LMNA (0.63) | LMNAKDM4EALDH1A1CYP1A2TSHR | |
| SCHEMBL12346332 | 0.83 | LMNA (0.63) | LMNAKDM4EALDH1A1CYP1A2TSHR | |
| SCHEMBL16015176 | 0.81 | LMNA (0.61) | LMNAKDM4EALDH1A1CYP1A2TSHR | |
| SCHEMBL20310245 | 0.81 | LMNA (0.61) | LMNAKDM4EALDH1A1CYP1A2TSHR | |
| SCHEMBL23748342 | 0.81 | LMNA (0.61) | LMNAKDM4EALDH1A1CYP1A2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 421 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11834425-B2 | Full continuous-flow preparation method of vitamin B1 | FUDAN UNIVERSITY (CN) | 2023-12-05 | — | — | US | claimed |
| CN-116283952-A | Vitamin B 1 Is a fully continuous flow preparation method | 复旦大学 | 2023-06-23 | — | — | CN | claimed |
| US-20230183196-A1 | FULL CONTINUOUS-FLOW PREPARATION METHOD OF VITAMIN B1 | FUDAN UNIVERSITY (CN) | 2023-06-15 | — | — | US | claimed |
| US-11554356-B2 | Full continuous flow preparation method of 2-methyl-4-amino-5-aminomethylpyrimidine | FUDAN UNIVERSITY (CN) | 2023-01-17 | — | — | US | claimed |
| US-11554354-B2 | Micro-reaction system and method for preparing 2-methyl-4-amino-5-aminomethyl pyrimidine | FUDAN UNIVERSITY (CN) | 2023-01-17 | — | — | US | claimed |
| CN-112611819-B | Method for measuring related substances in benfotiamine raw material and preparation thereof | 上海日馨医药科技股份有限公司 | 2022-09-06 | — | — | CN | claimed |
| CN-112341395-B | Micro-reaction system and method for continuously preparing 2-methyl-4-amino-5-aminomethyl pyrimidine by using same | 复旦大学 | 2022-06-21 | — | — | CN | claimed |
| CN-114163389-A | Preparation process of 2-methyl-4-amino-5-aminomethyl pyrimidine and methyl formate | 江苏兄弟维生素有限公司 | 2022-03-11 | — | — | CN | claimed |
| US-20210394150-A1 | FULL CONTINUOUS FLOW PREPARATION METHOD OF 2-METHYL-4-AMINO-5-AMINOMETHYLPYRIMIDINE | UNIV FUDAN (CN) | 2021-12-23 | — | — | US | claimed |
| US-20210394148-A1 | MICRO-REACTION SYSTEM AND METHOD FOR PREPARING 2-METHYL-4-AMINO-5-AMINOMETHYL PYRIMIDINE | FUDAN UNIVERSITY (CN) | 2021-12-23 | — | — | US | claimed |
| US-20020040141-A1 | Preparation of 2-methyl-4-amino-5-aminomethylpyrimidine | BASF AKTIENGESELLSCHAFT (DE) | 2002-04-04 | — | — | US | claimed |
| US-6365740-B1 | REACTING 2-METHYL-4-AMINO-5-ALKOXYMETHYLPYRIMIDINE COMPOUND WITH AMMONIA IN PRESENCE OF CATALYST TO FORM 2-METHYL-4-AMINO-5-AMINOMETHYLPYRIMIDINE | BASF AKTIENGESELLSCHAFT (DE) | 2002-04-02 | — | — | US | claimed |
| EP-1138675-A2 | Process for the preparation of 2-methyl-4-amino-5-aminomethylpyrimidine | BASF AKTIENGESELLSCHAFT (DE) | 2001-10-04 | — | — | EP | claimed |
| EP-0290888-B1 | 2-Methyl-4-amino-5-aminomethyl-pyrimidine carbonate, process for preparing the same and method of purification of 2-methyl-4-amino-5-aminomethylpyrimidine using the same | UBE INDUSTRIES (JP) | 1994-01-26 | — | — | EP | claimed |
| EP-0566698-A1 | AMINO-SUBSTITUTED PYRIMIDINES, DERIVATIVES AND METHODS OF USE THEREFOR | THE ROCKEFELLER UNIVERSITY (US) | 1993-10-27 | — | — | EP | claimed |
| WO-1992011853-A1 | AMINO-SUBSTITUTED PYRIMIDINES, DERIVATIVES AND METHODS OF USE THEREFOR | THE ROCKEFELLER UNIVERSITY (US) | 1992-07-23 | — | — | WO | claimed |
| US-5114943-A | Aging resistance of proteins to prevent food spoilage | THE ROCKEFELLER UNIVERSITY (US) | 1992-05-19 | — | — | US | claimed |
| US-5037982-A | Salt formation with carbon dioxide, heating to recover pure form with solvent | UBE INDUSTRIES, LTD. (JP) | 1991-08-06 | — | — | US | claimed |
| EP-0290888-A2 | 2-Methyl-4-amino-5-aminomethyl-pyrimidine carbonate, process for preparing the same and method of purification of 2-methyl-4-amino-5-aminomethylpyrimidine using the same | UBE INDUSTRIES, LTD. (JP) | 1988-11-17 | — | — | EP | claimed |
| US-4256550-A | ELECTROCHEMICAL OXIDATION AND REDUCTION | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1981-03-17 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210394148-A1 | MICRO-REACTION SYSTEM AND METHOD FOR PREPARING 2-METHYL-4-AMINO-5-AMINOMETHYL PYRIMIDINE | DPYD, HNMT, KIT | LMNA 3506/4885KDM4E 797/4885ALDH1A1 3874/4885 |
| US-20230183196-A1 | FULL CONTINUOUS-FLOW PREPARATION METHOD OF VITAMIN B1 | SLC19A2, VKORC1, VKORC1L1 | LMNA 1178/4885KDM4E 4050/4885ALDH1A1 390/4885 |
| US-20210394150-A1 | FULL CONTINUOUS FLOW PREPARATION METHOD OF 2-METHYL-4-AMINO-5-AMINOMETHYLPYRIMIDINE | MCM4, NUDT1, CMPK1 | LMNA 4202/4885KDM4E 287/4885ALDH1A1 1195/4885 |
| US-11834425-B2 | Full continuous-flow preparation method of vitamin B1 | SLC19A2, CYP2S1, CBS | LMNA 4424/4885KDM4E 2847/4885ALDH1A1 670/4885 |
| US-11554356-B2 | Full continuous flow preparation method of 2-methyl-4-amino-5-aminomethylpyrimidine | MCM4, NUDT1, CMPK1 | LMNA 4202/4885KDM4E 287/4885ALDH1A1 1195/4885 |
| US-20020040141-A1 | Preparation of 2-methyl-4-amino-5-aminomethylpyrimidine | DPYD, DNMT1, TPMT | LMNA 3550/4885KDM4E 478/4885ALDH1A1 461/4885 |
| US-11554354-B2 | Micro-reaction system and method for preparing 2-methyl-4-amino-5-aminomethyl pyrimidine | DPYD, HNMT, KIT | LMNA 3506/4885KDM4E 797/4885ALDH1A1 3874/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.