SCHEMBL1059083

SCHEMBL1059083

NCC=C(C(=O)CN)C(=O)CN

nearest known ligand 0.40

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
GABRR1 P24046 3/20 0.40
ABAT P80404 1/20 0.37
GLRA1 P23415 1/20 0.35
SLC6A9 P48067 1/20 0.35
OR51E2 Q9H255 1/20 0.35
GABRR2 P28476 2/20 0.32
BLM P54132 2/20 0.32
GABRR3 A8MPY1 1/20 0.32
LMNA P02545 1/20 0.32
TSHR P16473 1/20 0.32
APEX1 P27695 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10883403 0.73 GABRR1 (0.55) GABRR1ABATGLRA1SLC6A9OR51E2
SCHEMBL9573120 0.71 GABRR1 (0.40) GABRR1ABATGABRR2BLMGABRR3
SCHEMBL6474897 0.69
SCHEMBL9227802 0.65 GLRA1 (0.30) GLRA1SLC6A9OR51E2
SCHEMBL2233971 0.65 GABRR1 (0.36) GABRR1ABAT
SCHEMBL9227817 0.65 GLRA1 (0.30) GLRA1SLC6A9OR51E2
SCHEMBL31258772 0.63 GLRA1 (0.47) GABRR1GLRA1SLC6A9OR51E2
SCHEMBL1496478 0.63 GLRA1 (0.47) GABRR1GLRA1SLC6A9OR51E2
SCHEMBL2090005 0.61
SCHEMBL6014537 0.61

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3141615-B1 REAL-TIME NUCLEIC ACID DETECTION PROCESSES AND COMPOSITIONS ENZO LIFE SCIENCES INC (US) 2019-10-23 EP disclosed
US-20190048401-A1 OPTIMIZED REAL-TIME NUCLEIC ACID DETECTION PROCESSES ENZO LIFE SCIENCES, INC. (US) 2019-02-14 US disclosed
EP-1348713-B1 Labeling reagents and labeled targets, target labeling processes and other processes for using same in nucleic acid determinations and analyses ENZO LIFE SCIENCES INC (US) 2019-01-23 EP disclosed
US-10144957-B2 Optimized real time nucleic acid detection processes ENZO LIFE SCIENCES, INC. (US) 2018-12-04 US disclosed
US-10144956-B2 Processes for quantitative or qualitative detection of single-stranded or double-stranded nucleic acids ENZO BIOCHEM, INC. (US) 2018-12-04 US disclosed
EP-2366798-B1 Nucleic acid detection process involving energy transfer labels on nucleotide ENZO LIFE SCIENCES INC (US) 2017-06-28 EP disclosed
EP-1344835-B1 REAL-TIME NUCLEIC ACID DETECTION PROCESSES AND COMPOSITIONS ENZO LIFE SCIENCES INC (US) 2017-06-14 EP disclosed
EP-3141615-A1 REAL-TIME NUCLEIC ACID DETECTION PROCESSES AND COMPOSITIONS Enzo Life Sciences, Inc. (US) 2017-03-15 EP disclosed
US-20160281146-A1 OPTIMIZED REAL TIME NUCLEIC ACID DETECTION PROCESSES ENZO LIFE SCIENCES, INC. (US) 2016-09-29 US disclosed
US-20160273028-A1 PROCESSES FOR QUANTITATIVE OR QUALITATIVE DETECTION OF SINGLE-STRANDED OR DOUBLE-STRANDED NUCLEIC ACIDS ENZO LIFE SCIENCES, INC. (US) 2016-09-22 US disclosed
US-20050004350-A1 Novel chemiluminescent reagents ENZO LIFE SCIENCES, INC. (US) 2005-01-06 US disclosed
US-20040254355-A1 Labeling reagents comprising aphenylic analogs of rhodamine dyes ENZO LIFE SCIENCES, INC. 2004-12-16 US disclosed
US-20040229248-A1 Novel dye labeling composition ENZO LIFE SCIENCES, INC. 2004-11-18 US disclosed
US-20040230036-A1 Heterodimeric dye composition ENZO LIFE SCIENCES, INC. (US) 2004-11-18 US disclosed
US-20040203038-A1 Process for preparing novel cyanine dye labeling reagents ENZO LIFE SCIENCES, INC. 2004-10-14 US disclosed
US-20040192893-A1 comprises cyanine dyes, xanthene dyes, porphyrin dyes, coumarin dyes or composite dyes for use in labeling nucleic acids or proteins in assay, and as diagnostic aid in genomics/proteomics ENZO LIFE SCIENCES, INC. (US) 2004-09-30 US disclosed
US-20040176586-A1 Process for detecting the presence or quantity of enzymatic activity in a sample ENZO LIFE SCIENCES, INC. (US) 2004-09-09 US disclosed
US-20030225247-A1 Labeling reagents and labeled targets, target labeling processes and other processes for using same in nucleic acid determinations and analyses ENZO LIFE SCIENCES, INC. 2003-12-04 US disclosed
EP-1348713-A2 Labeling reagents and labeled tabeled targets, target labeling processes and other processes for using same in nucleic acid determinations and analyses Enzo Life Sciences, Inc. (US) 2003-10-01 EP disclosed
EP-1344835-A2 Real-time nucleic acid detection processes and compositions Enzo Life Sciences, Inc. (US) 2003-09-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040229248-A1 Novel dye labeling composition IK, PHAX, CHLSN GABRR1 4612/4885ABAT 1244/4885GLRA1 4156/4885
US-20040203038-A1 Process for preparing novel cyanine dye labeling reagents PHAX, IK, CHLSN GABRR1 4655/4885ABAT 1513/4885GLRA1 4264/4885
US-20050004350-A1 Novel chemiluminescent reagents CHLSN, CYBA, HLCS GABRR1 4592/4885ABAT 1039/4885GLRA1 4155/4885
US-20040176586-A1 Process for detecting the presence or quantity of enzymatic activity in a sample RNGTT, POLRMT, CHLSN GABRR1 4490/4885ABAT 1056/4885GLRA1 4552/4885
US-20040230036-A1 Heterodimeric dye composition IK, CHLSN, CRY2 GABRR1 4277/4885ABAT 2009/4885GLRA1 3440/4885
US-20030225247-A1 Labeling reagents and labeled targets, target labeling processes and other processes for using same in nucleic acid determinations and analyses POLRMT, CHLSN, PHAX GABRR1 4542/4885ABAT 634/4885GLRA1 3865/4885
US-20040254355-A1 Labeling reagents comprising aphenylic analogs of rhodamine dyes IK, RBM25, CHLSN GABRR1 4304/4885ABAT 565/4885GLRA1 2615/4885
US-20040192893-A1 comprises cyanine dyes, xanthene dyes, porphyrin dyes, coumarin dyes or composite dyes for use in labeling nucleic acids or proteins in assay, and as diagnostic aid in genomics/proteomics CHLSN, DDB1, PROC GABRR1 4734/4885ABAT 2418/4885GLRA1 4308/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.